AB44G_ORYSJ
ID AB44G_ORYSJ Reviewed; 1456 AA.
AC Q6YW62; Q0J5Z9;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 24-JUN-2015, sequence version 2.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=ABC transporter G family member 44 {ECO:0000303|PubMed:18299247};
DE Short=OsABCG44 {ECO:0000303|PubMed:18299247};
DE AltName: Full=Pleiotropic drug resistance protein 17 {ECO:0000303|PubMed:16506311};
DE Short=OsPDR17 {ECO:0000303|PubMed:16506311};
GN Name=ABCG44 {ECO:0000303|PubMed:18299247};
GN Synonyms=PDR17 {ECO:0000303|PubMed:16506311};
GN OrderedLocusNames=Os08g0384500 {ECO:0000312|EMBL:BAF23616.1},
GN LOC_Os08g29570; ORFNames=B1090H08.39 {ECO:0000312|EMBL:BAD05827.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 694-1456.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT "Organization and function of the plant pleiotropic drug resistance ABC
RT transporter family.";
RL FEBS Lett. 580:1123-1130(2006).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD05827.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF23616.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP005795; BAD05827.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008214; BAF23616.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK100858; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015650488.1; XM_015795002.1.
DR AlphaFoldDB; Q6YW62; -.
DR SMR; Q6YW62; -.
DR STRING; 4530.OS08T0384500-01; -.
DR PaxDb; Q6YW62; -.
DR PRIDE; Q6YW62; -.
DR GeneID; 4345450; -.
DR KEGG; osa:4345450; -.
DR eggNOG; KOG0065; Eukaryota.
DR InParanoid; Q6YW62; -.
DR OrthoDB; 324553at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1456
FT /note="ABC transporter G family member 44"
FT /id="PRO_0000433454"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 571..591
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 626..646
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 658..678
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 682..702
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 768..788
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1202..1222
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1242..1262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1290..1310
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1317..1337
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1347..1367
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1378..1398
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1425..1445
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 169..442
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 520..733
FT /note="ABC transmembrane type-2 1"
FT /evidence="ECO:0000305"
FT DOMAIN 858..1110
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1183..1397
FT /note="ABC transmembrane type-2 2"
FT /evidence="ECO:0000305"
FT REGION 812..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..839
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 202..209
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 903..910
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 1456 AA; 162870 MW; 6D398D48D6C42DEC CRC64;
MDTGEAAFGV ASLRLRGSMA SASSRRAPSY RDYDVFSIAS SSRAEAEDDE EALKWAALEK
LPTHARVRKG IVAAADDGQG SGAAGEVVDV AGLGFQERKH LLERLVRVAE EDHESFLLKL
KQRIDRVGLD FPTIEVRYEH LSIDALAHVG SRGLPTFLNT TLNSLESLAN LLHVVPNKKR
PLNILHDVHG VIKPRRMTLL LGPPGSGKTT LLLALAGKLG SDLKVSGKVT YNGYGMDEFV
AQRSAAYISQ HDLHIPEMTV RETLAFSARC QGVGTRYDML TELARREKAA NIKPDPDLDV
YMKAISVGGQ ETNIITDYVL KILGLDICAD TIVGNEMLRG ISGGQRKRVT TGEMIVGPAR
AMFMDEISTG LDSSTTFQIV KSLGQITSIL GGTTVISLLQ PAPETYNLFD DIILLSDGHI
VYQGPREHVL EFFESMGFKC PDRKGVADFL QEVTSRKDQQ QYWARTHQPY RYIPVQEFAC
AFQSFHVGQT LSDELSHPFD KSTSHPASLT TSTYGASKLE LLRTCIAREL LLMKRNMFVY
RFRAFQLLVI TIIVMTLFLR TNMHHETRTD GIVYLGALFF AMVAHMFNGF SELAMATIKL
PVFFKQRDYL FFPSWAYTIP TWILKIPISC FEVAITVFLS YYVIGFDPNV GRLFKQYLLL
LLVNQMAAAL FRFIAALGRT MVVANTLASF ALLVLLVLSG FILSHHDVKK WWIWGYWISP
LQYAMNAIAV NEFLGHKWNR LVQGTNTTLG IEVLKSRGMF TEAKWYWIGV GALFGYVIVF
NILFTIALGY LKPSGKAQQI LSEEALKEKH ANITGETIND PRNSASSGQT TNTRRNAAPG
EASENRRGMV LPFAPLAVAF NNIRYSVDMP PEMKAQGVDQ DRLLLLKGVS GSFRPGVLTA
LMGVSGAGKT TLMDVLAGRK TGGYIEGDIS ISGYPKKQET FARVSGYCEQ NDIHSPNVTV
YESLAYSAWL RLPSDVDSET RKMFIEQVME LVELNPLRDA LVGLPGVNGL STEQRKRLTI
AVELVANPSI IFMDEPTSGL DARAAAIVMR TVRNTVDTGR TVVCTIHQPS IDIFEAFDEL
FLMKRGGEEI YVGPLGHHSC DLIEYFEGVE GVSKIKPGYN PATWMLEVTT LAQEDVLGIS
FTDVYKNSDL YQRNQSLIKG ISRPPQGSKD LFFPTQFSQS FSTQCMACLW KQNLSYWRNP
PYTVVRFFFS LIVALMFGTI FWRLGSKRSR QQDLFNAMGS MYAAVLFMGI SYSSSVQPVV
AVERTVFYRE RAAGMYSALP YAFGQVVVEL PYVLVQSAVY GVIVYAMIGF EWEAKKFFWY
LYFMYFTLLY FTFYGMLAVG LTPSYNIASI VSSFFYGIWN LFSGFVIPRP SMPVWWRWYS
WACPVSWTLY GLVASQFGDL KEPLRDTGVP IDVFLREYFG FKHDFLGVVA VAVAGFATLF
AVSFSLSIKM LNFQRR
