ID   RPOE_STAA8              Reviewed;         176 AA.
AC   Q2FWD0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Probable DNA-directed RNA polymerase subunit delta {ECO:0000255|HAMAP-Rule:MF_00357};
DE   AltName: Full=RNAP delta factor {ECO:0000255|HAMAP-Rule:MF_00357};
GN   Name=rpoE {ECO:0000255|HAMAP-Rule:MF_00357};
GN   OrderedLocusNames=SAOUHSC_02369;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- FUNCTION: Participates in both the initiation and recycling phases of
CC       transcription. In the presence of the delta subunit, RNAP displays an
CC       increased specificity of transcription, a decreased affinity for
CC       nucleic acids, and an increased efficiency of RNA synthesis because of
CC       enhanced recycling. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC   -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC       subunits. The core is associated with a delta subunit and one of
CC       several sigma factors. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC   -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00357}.
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DR   EMBL; CP000253; ABD31400.1; -; Genomic_DNA.
DR   RefSeq; WP_000701483.1; NZ_LS483365.1.
DR   RefSeq; YP_500845.1; NC_007795.1.
DR   AlphaFoldDB; Q2FWD0; -.
DR   SMR; Q2FWD0; -.
DR   STRING; 1280.SAXN108_2373; -.
DR   EnsemblBacteria; ABD31400; ABD31400; SAOUHSC_02369.
DR   GeneID; 3919412; -.
DR   GeneID; 66840334; -.
DR   KEGG; sao:SAOUHSC_02369; -.
DR   PATRIC; fig|93061.5.peg.2146; -.
DR   eggNOG; COG3343; Bacteria.
DR   HOGENOM; CLU_116648_1_0_9; -.
DR   OMA; TWGLRSW; -.
DR   PRO; PR:Q2FWD0; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.1250; -; 1.
DR   HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR   InterPro; IPR007759; Asxl_HARE-HTH.
DR   InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR   InterPro; IPR029757; RpoE.
DR   Pfam; PF05066; HARE-HTH; 1.
DR   TIGRFAMs; TIGR04567; RNAP_delt_lowGC; 1.
DR   PROSITE; PS51913; HTH_HARE; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..176
FT                   /note="Probable DNA-directed RNA polymerase subunit delta"
FT                   /id="PRO_0000303138"
FT   DOMAIN          14..81
FT                   /note="HTH HARE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
FT   REGION          114..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   176 AA;  20881 MW;  D7A72313DA512D89 CRC64;
     MKIQDYTKQM VDEKSFIDMA YTLLNDKGET MNLYDIIDEF RALGDYEYEE IENRVVQFYT
     DLNTDGRFLN VGENLWGLRD WYSVDDIEEK IAPTIQKFDI LDADDEEDQN LKLLGEDEMD
     DDDDIPAQTD DQEELNDPED EQVEEEINHS DIVIEEDEDE LDEDEEVFED EEDFND