ID   RPOE_STRSY              Reviewed;         193 AA.
AC   A4VT63;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Probable DNA-directed RNA polymerase subunit delta {ECO:0000255|HAMAP-Rule:MF_00357};
DE   AltName: Full=RNAP delta factor {ECO:0000255|HAMAP-Rule:MF_00357};
GN   Name=rpoE {ECO:0000255|HAMAP-Rule:MF_00357}; OrderedLocusNames=SSU05_0334;
OS   Streptococcus suis (strain 05ZYH33).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=391295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05ZYH33;
RX   PubMed=17375201; DOI=10.1371/journal.pone.0000315;
RA   Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F., Pan X.,
RA   Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z., Ju A., Ge J.,
RA   Dong Y., Sun W., Jiang Y., Wang J., Yan J., Yang H., Wang X., Gao G.F.,
RA   Yang R., Wang J., Yu J.;
RT   "A glimpse of streptococcal toxic shock syndrome from comparative genomics
RT   of S. suis 2 Chinese isolates.";
RL   PLoS ONE 2:E315-E315(2007).
CC   -!- FUNCTION: Participates in both the initiation and recycling phases of
CC       transcription. In the presence of the delta subunit, RNAP displays an
CC       increased specificity of transcription, a decreased affinity for
CC       nucleic acids, and an increased efficiency of RNA synthesis because of
CC       enhanced recycling. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC   -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC       subunits. The core is associated with a delta subunit and one of
CC       several sigma factors. {ECO:0000255|HAMAP-Rule:MF_00357}.
CC   -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00357}.
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DR   EMBL; CP000407; ABP89302.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4VT63; -.
DR   SMR; A4VT63; -.
DR   STRING; 391295.SSU05_0334; -.
DR   EnsemblBacteria; ABP89302; ABP89302; SSU05_0334.
DR   KEGG; ssu:SSU05_0334; -.
DR   eggNOG; COG3343; Bacteria.
DR   HOGENOM; CLU_116648_0_0_9; -.
DR   OMA; TWGLRSW; -.
DR   Proteomes; UP000000243; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.1250; -; 1.
DR   HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR   InterPro; IPR007759; Asxl_HARE-HTH.
DR   InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR   InterPro; IPR029757; RpoE.
DR   Pfam; PF05066; HARE-HTH; 1.
DR   TIGRFAMs; TIGR04567; RNAP_delt_lowGC; 1.
DR   PROSITE; PS51913; HTH_HARE; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..193
FT                   /note="Probable DNA-directed RNA polymerase subunit delta"
FT                   /id="PRO_0000303145"
FT   DOMAIN          14..83
FT                   /note="HTH HARE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
FT   REGION          117..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..193
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   193 AA;  22277 MW;  4CED3A0A572B55DF CRC64;
     MELNVFAGQE KSELSMIEVA RAILEERGRD NEMYFNDLVN EIQNYLEKSN SEIRAALPTF
     YSDLNVDGSF IPLGENKWGL RSWYAIDEID EEVITLEEDD EDAPKRKKKR VNAFMDGDDD
     AIDYGHDDPE DEDNYPGSVS SEYDDENPDD EKDEVESYDS EINEIIPDDE LDEEDVDLGE
     DDDEYSDEEV VDE