ID   RPOF_KITAU              Reviewed;         297 AA.
AC   P37970;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=RNA polymerase sigma-F factor;
GN   Name=sigF; Synonyms=rpoX;
OS   Kitasatospora aureofaciens (Streptomyces aureofaciens).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Kitasatospora.
OX   NCBI_TaxID=1894;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7476207; DOI=10.1111/j.1365-2958.1995.mmi_17010037.x;
RA   Potuckova L., Kelemen G.H., Findlay K.C., Lonetto M.A., Buttner M.J.,
RA   Kormanec J.;
RT   "A new RNA polymerase sigma factor, sigma F, is required for the late
RT   stages of morphological differentiation in Streptomyces spp.";
RL   Mol. Microbiol. 17:37-48(1995).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is required for normal spore maturation.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. SigB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; L09565; AAA93050.1; -; Genomic_DNA.
DR   AlphaFoldDB; P37970; -.
DR   SMR; P37970; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014322; RNA_pol_sigma-B/F/G.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02980; SigBFG; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Sigma factor; Transcription; Transcription regulation.
FT   CHAIN           1..297
FT                   /note="RNA polymerase sigma-F factor"
FT                   /id="PRO_0000093979"
FT   DNA_BIND        264..283
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           101..114
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   297 AA;  33381 MW;  19F72E4DFA1445F7 CRC64;
     MTVPASTAPQ VPPQQDPQVP HPQEPREEPH EEPPSPPAAP RPQSRGADTR ALTQVLFGQL
     KGLQPGTREH ERVRGALIEA NLPLVRYAAA RFRSRNEPME DVVQVGTIGL INAIDRFDPE
     RGVQFPTFAM PTVVGEIKRY FRDNVRTVHV PRRLHELWVQ VNAATEDLTT LHGRTPTTPE
     IAERLRISED EVLSCIEAGR SYHATSLEAA QEGDGMPGLL DRLGYEDPEL AGVEHRDLVR
     HLLVQLPERE QRILLLRYYN NLTQSQISAE LGVSQMHVSR LLARSFARLR SANRIEA