ID   RPOP_GELSP              Reviewed;         831 AA.
AC   O03685;
DT   04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Probable DNA-directed RNA polymerase;
DE            EC=2.7.7.6;
OS   Gelasinospora sp. (strain G114).
OG   Mitochondrion.
OG   Plasmid Gel-kalDNA.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Gelasinospora;
OC   unclassified Gelasinospora.
OX   NCBI_TaxID=42248;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8821662; DOI=10.1007/bf02221579;
RA   Yuewang W., Yang X., Griffiths A.J.;
RT   "Structure of a Gelasinospora linear plasmid closely related to the kalilo
RT   plasmid of Neurospora intermedia.";
RL   Curr. Genet. 29:150-158(1996).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10031,
CC         ECO:0000255|PROSITE-ProRule:PRU10032};
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phage and mitochondrial RNA polymerase
CC       family. {ECO:0000305}.
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DR   EMBL; L40494; AAB41448.1; -; Genomic_DNA.
DR   PIR; S62751; S62751.
DR   AlphaFoldDB; O03685; -.
DR   SMR; O03685; -.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR002092; DNA-dir_Rpol_phage-type.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   PANTHER; PTHR10102; PTHR10102; 1.
DR   Pfam; PF00940; RNA_pol; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
DR   PROSITE; PS00900; RNA_POL_PHAGE_1; 1.
DR   PROSITE; PS00489; RNA_POL_PHAGE_2; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Mitochondrion; Nucleotidyltransferase;
KW   Plasmid; Transcription; Transferase.
FT   CHAIN           1..831
FT                   /note="Probable DNA-directed RNA polymerase"
FT                   /id="PRO_0000087755"
FT   ACT_SITE        490
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        560
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        738
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   831 AA;  96881 MW;  C256E06D15AFD889 CRC64;
     MECIERLRRK RTEYLFKNFI MIKFSFFNYR INMRNFHATS LRFIKFNYSA IKNIRNFSTE
     KKSEPKLSLF LTNISKILSE HKKDLYKAQE IIETEWLKLA TPSIDVKSDI KSTMYAKQRL
     IHGRAFDLLK LYKSNGNLNK ISKSLKDYIV NEKFIFIAWS YLLASYSKSS LPNLDYRIGY
     SITRHIYRES YKNDFMSFED FPEYNKFDLG FFVKLGDIFI NTFTSPLNPI FERVFENEIY
     SLKINKEYEY EIMESLVISP KALPMVCPPL IWWHGIRGGS VINLNDNADD SLVVGSFHHS
     HKIAISDKLY SVINKLNAFK FKINADLLSY LQNEGSFIID FYKKTKKDTY INNMITLDIA
     KTYLNTPFYL NVNIDWRGRI YTQSFYLGYQ GSELSLALIN LFEGQKLDEE GLFFFYVYGA
     NIYNEGGKFS KKSFQDRFNW VVENLDNIIA MDKDFILKAE SPTLFAAFCL TMRKLKENPD
     HPVFNPIFLD ATCSGVQHFA AMLLDLELGK YVNLINSGES VNDFYSQLIP AINKAINESA
     EKKLKNVKFS DISLNRSLLK KVIMTKSYNV TTYGITEQLK SKLEKVEKII ISKGKEIKVY
     DYLVPTKNGK FVVLDTFEVE TLASIINDNI FNQFPKLHSI YEYLTRLTKI YLKLDIPISC
     STPDGLELTQ RYNLSKVQKL TINFLGKNRT AVLRSWVSDK DSRREVPAII PNIIHSLDAA
     HLPMLIDSWD SYILPIHDCF GTHPNDMFKL AEQVRECFIL LYSKNDFLSK IDSKFRENLK
     DYKIEIVNKN GEDFVKIKGT PRYDYLPLPV LPQMGELNVE DIRDMGKYMI S