ID   RPOS_SALDU              Reviewed;         330 AA.
AC   P0A2E7; P37400; P39699; Q56132; Q93V26; Q9RN87; Q9RN91; Q9RN92; Q9RN93;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=RNA polymerase sigma factor RpoS {ECO:0000255|HAMAP-Rule:MF_00959};
DE   AltName: Full=Sigma S {ECO:0000255|HAMAP-Rule:MF_00959};
DE   AltName: Full=Sigma-38 {ECO:0000255|HAMAP-Rule:MF_00959};
GN   Name=rpoS {ECO:0000255|HAMAP-Rule:MF_00959}; Synonyms=katF;
OS   Salmonella dublin.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=98360;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Lane;
RX   PubMed=9023230; DOI=10.1128/jb.179.4.1409-1412.1997;
RA   El-Gedaily A., Paesold G., Chen C.Y., Guiney D.G., Krause M.W.;
RT   "Plasmid virulence gene expression induced by short-chain fatty acids in
RT   Salmonella dublin: identification of rpoS-dependent and rpo-S-independent
RT   mechanisms.";
RL   J. Bacteriol. 179:1409-1412(1997).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is the master transcriptional regulator of
CC       the stationary phase and the general stress response.
CC       {ECO:0000255|HAMAP-Rule:MF_00959}.
CC   -!- SUBUNIT: Interacts with the RNA polymerase core enzyme.
CC       {ECO:0000255|HAMAP-Rule:MF_00959}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00959}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoS subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00959}.
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DR   EMBL; X82129; CAA57640.1; -; Genomic_DNA.
DR   RefSeq; WP_000081498.1; NZ_VDCP01000001.1.
DR   AlphaFoldDB; P0A2E7; -.
DR   SMR; P0A2E7; -.
DR   GeneID; 58317824; -.
DR   GeneID; 64173183; -.
DR   GeneID; 67517453; -.
DR   PATRIC; fig|98360.39.peg.2647; -.
DR   OMA; RRVQREF; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_00959; Sigma70_RpoS; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR012761; RNA_pol_sigma_RpoS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02394; rpoS_proteo; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Sigma factor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..330
FT                   /note="RNA polymerase sigma factor RpoS"
FT                   /id="PRO_0000093971"
FT   DNA_BIND        288..307
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          56..89
FT                   /note="Sigma-70 factor domain-1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          94..164
FT                   /note="Sigma-70 factor domain-2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          174..249
FT                   /note="Sigma-70 factor domain-3"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          262..315
FT                   /note="Sigma-70 factor domain-4"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   MOTIF           118..121
FT                   /note="Interaction with polymerase core subunit RpoC"
SQ   SEQUENCE   330 AA;  37933 MW;  4400E48DEB358ECC CRC64;
     MSQNTLKVHD LNEDAEFDEN GVEAFDEKAL SEEEPSDNDL AEEELLSQGA TQRVLDATQL
     YLGEIGYSPL LTAEEEVYFA RRALRGDVAS RRRMIESNLR LVVKIARRYG NRGLALLDLI
     EEGNLGLIRA VEKFDPERGF RFSTYATWWI RQTIERAIMN QTRTIRLPIH IVKELNVYLR
     TARELSHKLD HEPSAEEIAE QLDKPVDDVS RMLRLNERIT SVDTPLGGDS EKALLDILAD
     EKENGPEDTT QDDDMKQSIV KWLFELNAKQ REVLARRFGL LGYEAATLED VGREIGLTRE
     RVRQIQVEGL RRLREILQTQ GLNIEALFRE