ID   RPOS_YEREN              Reviewed;         331 AA.
AC   P47765;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=RNA polymerase sigma factor RpoS {ECO:0000255|HAMAP-Rule:MF_00959};
DE   AltName: Full=Sigma S {ECO:0000255|HAMAP-Rule:MF_00959};
DE   AltName: Full=Sigma-38 {ECO:0000255|HAMAP-Rule:MF_00959};
GN   Name=rpoS {ECO:0000255|HAMAP-Rule:MF_00959};
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=W1024 / Serotype O:9;
RX   PubMed=7729893; DOI=10.1128/iai.63.5.1840-1847.1995;
RA   Iriarte M., Stainier I., Cornelis G.R.;
RT   "The rpoS gene from Yersinia enterocolitica and its influence on expression
RT   of virulence factors.";
RL   Infect. Immun. 63:1840-1847(1995).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is the master transcriptional regulator of
CC       the stationary phase and the general stress response (By similarity).
CC       Required for the normal expression of the enterotoxin, yst, in the
CC       stationary phase. {ECO:0000255|HAMAP-Rule:MF_00959,
CC       ECO:0000269|PubMed:7729893}.
CC   -!- SUBUNIT: Interacts with the RNA polymerase core enzyme.
CC       {ECO:0000255|HAMAP-Rule:MF_00959}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00959}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoS subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00959}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U16152; AAC43391.1; -; Genomic_DNA.
DR   AlphaFoldDB; P47765; -.
DR   SMR; P47765; -.
DR   STRING; 1443113.LC20_04386; -.
DR   eggNOG; COG0568; Bacteria.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_00959; Sigma70_RpoS; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR012761; RNA_pol_sigma_RpoS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02394; rpoS_proteo; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Sigma factor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..331
FT                   /note="RNA polymerase sigma factor RpoS"
FT                   /id="PRO_0000093977"
FT   DNA_BIND        289..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          57..90
FT                   /note="Sigma-70 factor domain-1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          95..165
FT                   /note="Sigma-70 factor domain-2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          175..250
FT                   /note="Sigma-70 factor domain-3"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   REGION          263..316
FT                   /note="Sigma-70 factor domain-4"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00959"
FT   MOTIF           119..122
FT                   /note="Interaction with polymerase core subunit RpoC"
SQ   SEQUENCE   331 AA;  37968 MW;  1C6C9B07449B53E8 CRC64;
     MSQNTLKVNE LHEDADFDEN STETEIFDEK ALVEDEPTES ELAEDELLAQ GVTSGADATQ
     LYLGEIGYSP LLTAEEEVYF ARRALRGDVP SRRRMIESNL RLVVKIARRY SNRGLALLDL
     IEEGNLGLIR AVEKFDPERG FRFSTYATWW IRQTIERAIM NQTRTIRLPI HIVKELNVYL
     RTARELSHKL DHEPSAEEIA EQLDKPVDDV SRMLRLNERI TSVDTPLGGD SEKALLDILS
     DENENGPEDT TQDDDMKQSI VKWLFELNAK QREVLARRFG LLGYEAATLE DVGREIGLTR
     ERVRQIQVEG LRRLREILQA QGLSIEALFR E