RPOY_BACAN
ID RPOY_BACAN Reviewed; 70 AA.
AC Q81MQ7; Q6HU52; Q6KND5;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=DNA-directed RNA polymerase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
DE Short=RNAP epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01553};
DE AltName: Full=RNA polymerase epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE AltName: Full=Transcriptase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
GN Name=rpoY {ECO:0000255|HAMAP-Rule:MF_01553};
GN OrderedLocusNames=BA_4189, GBAA_4189, BAS3886;
OS Bacillus anthracis.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=1392;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ames / isolate Porton;
RX PubMed=12721629; DOI=10.1038/nature01586;
RA Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT related bacteria.";
RL Nature 423:81-86(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ames ancestor;
RX PubMed=18952800; DOI=10.1128/jb.01347-08;
RA Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL J. Bacteriol. 191:445-446(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sterne;
RA Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA Richardson P., Rubin E., Tice H.;
RT "Complete genome sequence of Bacillus anthracis Sterne.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: A non-essential component of RNA polymerase (RNAP).
CC {ECO:0000255|HAMAP-Rule:MF_01553}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01553};
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunit. The core is associated with a delta subunit, and at least one
CC of epsilon or omega. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01553}.
CC -!- SIMILARITY: Belongs to the RNA polymerase subunit epsilon family.
CC {ECO:0000255|HAMAP-Rule:MF_01553}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE016879; AAP27911.1; -; Genomic_DNA.
DR EMBL; AE017334; AAT33308.1; -; Genomic_DNA.
DR EMBL; AE017225; AAT56187.1; -; Genomic_DNA.
DR RefSeq; NP_846425.1; NC_003997.3.
DR RefSeq; WP_000576443.1; NZ_WXXJ01000027.1.
DR RefSeq; YP_030136.1; NC_005945.1.
DR AlphaFoldDB; Q81MQ7; -.
DR SMR; Q81MQ7; -.
DR STRING; 260799.BAS3886; -.
DR DNASU; 1088867; -.
DR EnsemblBacteria; AAP27911; AAP27911; BA_4189.
DR EnsemblBacteria; AAT33308; AAT33308; GBAA_4189.
DR GeneID; 45023864; -.
DR KEGG; ban:BA_4189; -.
DR KEGG; bar:GBAA_4189; -.
DR KEGG; bat:BAS3886; -.
DR PATRIC; fig|198094.11.peg.4158; -.
DR eggNOG; COG5503; Bacteria.
DR HOGENOM; CLU_187518_0_0_9; -.
DR OMA; TIYVEGE; -.
DR Proteomes; UP000000427; Chromosome.
DR Proteomes; UP000000594; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01553; RNApol_bact_RpoY; 1.
DR InterPro; IPR009907; RpoY.
DR Pfam; PF07288; RpoY; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..70
FT /note="DNA-directed RNA polymerase subunit epsilon"
FT /id="PRO_0000163114"
SQ SEQUENCE 70 AA; 8189 MW; 9BD0266151060F47 CRC64;
MIFKVFYQEK MTEVPVRENT KVLYLEATSE KDVRTKLNKF AYNIEFVQSV TGNHLEYEKA
NADLTLAEIV
