RPOY_LEUMM
ID RPOY_LEUMM Reviewed; 70 AA.
AC Q03VQ8;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=DNA-directed RNA polymerase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
DE Short=RNAP epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01553};
DE AltName: Full=RNA polymerase epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE AltName: Full=Transcriptase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
GN Name=rpoY {ECO:0000255|HAMAP-Rule:MF_01553}; OrderedLocusNames=LEUM_1622;
OS Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM
OS 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB
OS 8023 / NCTC 12954 / NRRL B-1118 / 37Y).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Leuconostoc.
OX NCBI_TaxID=203120;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523
RC / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y;
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T.,
RA Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC -!- FUNCTION: A non-essential component of RNA polymerase (RNAP).
CC {ECO:0000255|HAMAP-Rule:MF_01553}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01553};
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunit. The core is associated with a delta subunit, and at least one
CC of epsilon or omega. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription.
CC {ECO:0000255|HAMAP-Rule:MF_01553}.
CC -!- SIMILARITY: Belongs to the RNA polymerase subunit epsilon family.
CC {ECO:0000255|HAMAP-Rule:MF_01553}.
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DR EMBL; CP000414; ABJ62714.1; -; Genomic_DNA.
DR RefSeq; WP_011680267.1; NC_008531.1.
DR AlphaFoldDB; Q03VQ8; -.
DR SMR; Q03VQ8; -.
DR STRING; 203120.LEUM_1622; -.
DR EnsemblBacteria; ABJ62714; ABJ62714; LEUM_1622.
DR GeneID; 61175906; -.
DR KEGG; lme:LEUM_1622; -.
DR eggNOG; COG5503; Bacteria.
DR HOGENOM; CLU_187518_0_0_9; -.
DR OMA; TYEKANP; -.
DR OrthoDB; 2007787at2; -.
DR Proteomes; UP000000362; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01553; RNApol_bact_RpoY; 1.
DR InterPro; IPR009907; RpoY.
DR Pfam; PF07288; RpoY; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW Transferase.
FT CHAIN 1..70
FT /note="DNA-directed RNA polymerase subunit epsilon"
FT /id="PRO_1000068874"
SQ SEQUENCE 70 AA; 8425 MW; DE6FEB96BE8FD756 CRC64;
MIYKIYYQEH PERNPKRETT ISMYIEAESL PQAREIIEEN TEYNVEFIEE LSDKAVTYEK
ANPNFEVTTF