ID   RPOY_STRA5              Reviewed;          76 AA.
AC   Q8DXT6;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=DNA-directed RNA polymerase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
DE            Short=RNAP epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01553};
DE   AltName: Full=RNA polymerase epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE   AltName: Full=Transcriptase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
GN   Name=rpoY {ECO:0000255|HAMAP-Rule:MF_01553}; OrderedLocusNames=SAG1760;
OS   Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=208435;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-611 / 2603 V/R;
RX   PubMed=12200547; DOI=10.1073/pnas.182380799;
RA   Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.N.,
RA   Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D.,
RA   Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA   DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Lewis M.R., Radune D.,
RA   Fedorova N.B., Scanlan D., Khouri H.M., Mulligan S., Carty H.A.,
RA   Cline R.T., Van Aken S.E., Gill J., Scarselli M., Mora M., Iacobini E.T.,
RA   Brettoni C., Galli G., Mariani M., Vegni F., Maione D., Rinaudo D.,
RA   Rappuoli R., Telford J.L., Kasper D.L., Grandi G., Fraser C.M.;
RT   "Complete genome sequence and comparative genomic analysis of an emerging
RT   human pathogen, serotype V Streptococcus agalactiae.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002).
CC   -!- FUNCTION: A non-essential component of RNA polymerase (RNAP).
CC       {ECO:0000255|HAMAP-Rule:MF_01553}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01553};
CC   -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC       subunit. The core is associated with a delta subunit, and at least one
CC       of epsilon or omega. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01553}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase subunit epsilon family.
CC       {ECO:0000255|HAMAP-Rule:MF_01553}.
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DR   EMBL; AE009948; AAN00623.1; -; Genomic_DNA.
DR   RefSeq; NP_688750.1; NC_004116.1.
DR   RefSeq; WP_000639570.1; NC_004116.1.
DR   AlphaFoldDB; Q8DXT6; -.
DR   SMR; Q8DXT6; -.
DR   STRING; 208435.SAG1760; -.
DR   EnsemblBacteria; AAN00623; AAN00623; SAG1760.
DR   GeneID; 66886598; -.
DR   KEGG; sag:SAG1760; -.
DR   PATRIC; fig|208435.3.peg.1766; -.
DR   HOGENOM; CLU_187518_0_0_9; -.
DR   OMA; TIYVEGE; -.
DR   Proteomes; UP000000821; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01553; RNApol_bact_RpoY; 1.
DR   InterPro; IPR009907; RpoY.
DR   Pfam; PF07288; RpoY; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..76
FT                   /note="DNA-directed RNA polymerase subunit epsilon"
FT                   /id="PRO_0000163145"
SQ   SEQUENCE   76 AA;  9107 MW;  B6F43525E5BE9F6F CRC64;
     MIYKVFYQET KERNPRREQT KTLYVTIDAA NELEGRIAAR KLVEENTAYN IEFIELLSDK
     HLEYEKETGV FELTEF