ID   RPOY_STRMU              Reviewed;          76 AA.
AC   Q8DVU6;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=DNA-directed RNA polymerase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
DE            Short=RNAP epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01553};
DE   AltName: Full=RNA polymerase epsilon subunit {ECO:0000255|HAMAP-Rule:MF_01553};
DE   AltName: Full=Transcriptase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01553};
GN   Name=rpoY {ECO:0000255|HAMAP-Rule:MF_01553}; OrderedLocusNames=SMU_369c;
OS   Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=210007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700610 / UA159;
RX   PubMed=12397186; DOI=10.1073/pnas.172501299;
RA   Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B.,
RA   Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S.,
RA   Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.;
RT   "Genome sequence of Streptococcus mutans UA159, a cariogenic dental
RT   pathogen.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002).
CC   -!- FUNCTION: A non-essential component of RNA polymerase (RNAP).
CC       {ECO:0000255|HAMAP-Rule:MF_01553}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01553};
CC   -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC       subunit. The core is associated with a delta subunit, and at least one
CC       of epsilon or omega. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000255|HAMAP-Rule:MF_01553}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase subunit epsilon family.
CC       {ECO:0000255|HAMAP-Rule:MF_01553}.
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DR   EMBL; AE014133; AAN58127.1; -; Genomic_DNA.
DR   RefSeq; NP_720821.1; NC_004350.2.
DR   RefSeq; WP_002268030.1; NC_004350.2.
DR   AlphaFoldDB; Q8DVU6; -.
DR   SMR; Q8DVU6; -.
DR   STRING; 210007.SMU_369c; -.
DR   PRIDE; Q8DVU6; -.
DR   EnsemblBacteria; AAN58127; AAN58127; SMU_369c.
DR   KEGG; smu:SMU_369c; -.
DR   PATRIC; fig|210007.7.peg.323; -.
DR   eggNOG; COG5503; Bacteria.
DR   HOGENOM; CLU_187518_0_0_9; -.
DR   OMA; TIYVEGE; -.
DR   PhylomeDB; Q8DVU6; -.
DR   Proteomes; UP000002512; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01553; RNApol_bact_RpoY; 1.
DR   InterPro; IPR009907; RpoY.
DR   Pfam; PF07288; RpoY; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..76
FT                   /note="DNA-directed RNA polymerase subunit epsilon"
FT                   /id="PRO_0000163146"
SQ   SEQUENCE   76 AA;  9075 MW;  ADC9785C638DE6C5 CRC64;
     MIYKVFYQET KDSSPRREQT KTLYLDIDAQ TELDGRIQAR QLVEEKIAYN IELIELLSDK
     HLEYEKETGA FQLTEF