位置:首页 > 蛋白库 > AB46G_ORYSJ
AB46G_ORYSJ
ID   AB46G_ORYSJ             Reviewed;        1440 AA.
AC   C7J6G6; B9G2Z6;
DT   24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT   24-JUN-2015, sequence version 2.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=ABC transporter G family member 46 {ECO:0000303|PubMed:18299247};
DE            Short=OsABCG46 {ECO:0000303|PubMed:18299247};
DE   AltName: Full=Pleiotropic drug resistance protein 21 {ECO:0000303|PubMed:16506311};
DE            Short=OsPDR21 {ECO:0000303|PubMed:16506311};
GN   Name=ABCG46 {ECO:0000303|PubMed:18299247};
GN   Synonyms=PDR21 {ECO:0000303|PubMed:16506311};
GN   OrderedLocusNames=Os09g0332360 {ECO:0000312|EMBL:BAH94510.1},
GN   LOC_Os09g16290; ORFNames=OsJ_28924 {ECO:0000312|EMBL:EEE69493.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA   Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT   "Organization and function of the plant pleiotropic drug resistance ABC
RT   transporter family.";
RL   FEBS Lett. 580:1123-1130(2006).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA   Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA   Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA   Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT   "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL   Trends Plant Sci. 13:151-159(2008).
CC   -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC       PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAH94510.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EEE69493.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP008215; BAH94510.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014965; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM000146; EEE69493.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; C7J6G6; -.
DR   SMR; C7J6G6; -.
DR   PaxDb; C7J6G6; -.
DR   PRIDE; C7J6G6; -.
DR   eggNOG; KOG0065; Eukaryota.
DR   InParanoid; C7J6G6; -.
DR   Proteomes; UP000000763; Chromosome 9.
DR   Proteomes; UP000007752; Chromosome 9.
DR   Proteomes; UP000059680; Chromosome 9.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03232; ABCG_PDR_domain2; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR029481; ABC_trans_N.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR043926; ABCG_dom.
DR   InterPro; IPR034003; ABCG_PDR_2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013581; PDR_assoc.
DR   Pfam; PF01061; ABC2_membrane; 2.
DR   Pfam; PF19055; ABC2_membrane_7; 1.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF14510; ABC_trans_N; 1.
DR   Pfam; PF08370; PDR_assoc; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1440
FT                   /note="ABC transporter G family member 46"
FT                   /id="PRO_0000433456"
FT   TRANSMEM        516..536
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        561..581
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        603..623
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        634..654
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        659..679
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        688..708
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        745..765
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1188..1208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1219..1236
FT                   /note="Helical"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        1271..1291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1302..1322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1332..1352
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1357..1377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1410..1430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          137..419
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          497..710
FT                   /note="ABC transmembrane type-2 1"
FT                   /evidence="ECO:0000305"
FT   DOMAIN          843..1095
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          1168..1382
FT                   /note="ABC transmembrane type-2 2"
FT                   /evidence="ECO:0000305"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          794..829
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        814..829
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         170..177
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         888..895
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   1440 AA;  162399 MW;  26B183A00CBEEC23 CRC64;
     MDDDVDAGEI YAVDRQREEG SASAAAFSRS PSTGRVDDDD DDLLTYGRSA RRMAALPAPA
     MPEGTELRRP VGGDVVGDDD YLRFLYKFKE LFDRVGIKLP TIEVRYKNLN VEAESYVGSR
     GLPTILNTYA NILKGLANTL HMTTRSKQKI SVLHNASGII KPHRMTLLLG SPGSGKTSLL
     LALAGTLPST VKVSGMITYN GHTMDKFIPQ RSAAYVSQHD LHMAELTVRE TINFSAKCQG
     VGHHYDLFLE LLRREEEENI TPDPETDIYL KAATTGEEKA EIVTNHILKI LRLDICADTI
     VGDNMLRGIS GGQKRCLDAH TAPNVDSAAE MLVTLGRALF MDEISNGLDS STTFQIVNTI
     QQTIHVLGGT AVIALLQPAP ETYELFDDII LLSDGQVVYS GPRDHVLEFF KSLGFKCLER
     IGVADFLQEV TSRKDQKQYW IHGDDTYRYI PVTVIAEAFQ CFHVGQAIRS ELAIPFDNSK
     SHIAALKTSK HGVNLKKILK ANIDREILLL KRKSFLYIFN ALQLTLVAII AMSVFIHTNM
     HHDSIENGRM YMGVQFFGTL AIMFKGLAEM GAALANLPVF FKQRDLLFYP AWTYSLPSWI
     IKTPISFLNT IIWVSITYYV IGFDPNIERC FRQFLVLFVM SEAICGLFRF IAALTRHPVV
     ASTVSEFCIL IVMVSSGFIL SRDEVKKWLI WEYWTSPLMY ALNALAVNEF LSPSWNEALP
     GFREPLGRLV LESRGVFPEA KWYWIGLGAL LGYVLLFNIL YTICLSILTL LKRNVREMSQ
     ETLQIKLENL TGYDQEPSSG GRVTNDKRYT EGGNNDEATS SNANHNSSPA RKGSILPFVP
     VYMTFEDIRY SIDMPKALKV QGMAGSRLEL LKDLSGSFRP GVLTALMGIS GAGKTTLLDV
     LAGRKTSGHI HGNITVSGYP KKQETFSRVS GYCEQNDIHS PNLTVYESLM FSAWLRLPAE
     IDSMARKRFI DEFMELVELF PLKDALVGLL GLSGLSTEQR KRLTIAVELV ANPSIIFMDE
     PTSGLDARAA AIVMRTVRNI VDMGRTVVCT IHQPSIDIFE SFDELFLMKR GGEAIYVGPL
     GQHSCELIKY FESIEGVRKI KHGYNPSTWM LEVTCTLQEQ ITGVNFTQVY KNSELYRRNK
     NLIKELSTPH DGSSDLLFPT KYSQTFVIQC LACLWKQRLS YWRNPPYIAV NFFFTVVIAL
     LFGTMFWGVG RKRQSQQALL SAMGSMYSTC FTLGVQNSSS VQPVVNIERT VFYRERASHM
     YSPLPYALGQ VVVELPYIFL QTLIYGVIVY SMMGYEWTCT KFFWYMFFMY FTLSYFTFYG
     MMAAGLTPNY TMSSIVSTTF YAIWHLFSGF LIPKTRIPIW WRWYYWICPV AWTINGLVTS
     QFGDVDDKFD NGVRVSDFVE SYFGYNLDLL WVAAMAVVSF AILFAILFGF SLKLFNFQKR
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024