ID   RPOZ_HELPY              Reviewed;          74 AA.
AC   P60325; O25467; Q9ZL67;
DT   02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   02-FEB-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=DNA-directed RNA polymerase subunit omega;
DE            Short=RNAP omega subunit;
DE            EC=2.7.7.6;
DE   AltName: Full=RNA polymerase omega subunit;
DE   AltName: Full=Transcriptase subunit omega;
GN   Name=rpoZ; OrderedLocusNames=HP_0776;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Promotes RNA polymerase assembly. Latches the N- and C-
CC       terminal regions of the beta' subunit thereby facilitating its
CC       interaction with the beta and alpha subunits (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta/beta' and
CC       1 omega subunit. When a sigma factor is associated with the core the
CC       holoenzyme is formed, which can initiate transcription (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase subunit omega family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD07826.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000511; AAD07826.1; ALT_INIT; Genomic_DNA.
DR   PIR; H64616; H64616.
DR   RefSeq; NP_207569.1; NC_000915.1.
DR   RefSeq; WP_000712202.1; NC_000915.1.
DR   AlphaFoldDB; P60325; -.
DR   SMR; P60325; -.
DR   IntAct; P60325; 9.
DR   MINT; P60325; -.
DR   STRING; 85962.C694_03985; -.
DR   PaxDb; P60325; -.
DR   EnsemblBacteria; AAD07826; AAD07826; HP_0776.
DR   GeneID; 66521994; -.
DR   KEGG; hpy:HP_0776; -.
DR   PATRIC; fig|85962.47.peg.828; -.
DR   eggNOG; COG1758; Bacteria.
DR   OMA; MMVSKRA; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.940.10; -; 1.
DR   HAMAP; MF_00366; RNApol_bact_RpoZ; 1.
DR   InterPro; IPR003716; DNA-dir_RNA_pol_omega.
DR   InterPro; IPR006110; Pol_omega/Rpo6/RPB6.
DR   InterPro; IPR036161; RPB6/omega-like_sf.
DR   Pfam; PF01192; RNA_pol_Rpb6; 1.
DR   SMART; SM01409; RNA_pol_Rpb6; 1.
DR   SUPFAM; SSF63562; SSF63562; 1.
DR   TIGRFAMs; TIGR00690; rpoZ; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..74
FT                   /note="DNA-directed RNA polymerase subunit omega"
FT                   /id="PRO_0000128943"
SQ   SEQUENCE   74 AA;  8505 MW;  C91E5A8499BEEE4A CRC64;
     MKKERTESLV AQALKNIGND RYMLDNLVFA RVKQLNAGAK TLVNMDPKRH KLVDIAIREI
     AEGKIDIDRI DERN