RPOZ_LACLA
ID RPOZ_LACLA Reviewed; 117 AA.
AC Q9CEE4;
DT 04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT 04-MAY-2001, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=DNA-directed RNA polymerase subunit omega;
DE Short=RNAP omega subunit;
DE EC=2.7.7.6;
DE AltName: Full=RNA polymerase omega subunit;
DE AltName: Full=Transcriptase subunit omega;
GN Name=rpoZ; OrderedLocusNames=LL1898; ORFNames=L149295;
OS Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=272623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL1403;
RX PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA Ehrlich S.D., Sorokin A.;
RT "The complete genome sequence of the lactic acid bacterium Lactococcus
RT lactis ssp. lactis IL1403.";
RL Genome Res. 11:731-753(2001).
CC -!- FUNCTION: Promotes RNA polymerase assembly. Latches the N- and C-
CC terminal regions of the beta' subunit thereby facilitating its
CC interaction with the beta and alpha subunits (By similarity).
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6;
CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC and 1 omega subunit. When a sigma factor is associated with the core
CC the holoenzyme is formed, which can initiate transcription (By
CC similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RNA polymerase subunit omega family.
CC {ECO:0000305}.
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DR EMBL; AE005176; AAK05996.1; -; Genomic_DNA.
DR PIR; B86862; B86862.
DR RefSeq; NP_268055.1; NC_002662.1.
DR RefSeq; WP_010906189.1; NC_002662.1.
DR AlphaFoldDB; Q9CEE4; -.
DR SMR; Q9CEE4; -.
DR STRING; 272623.L149295; -.
DR PaxDb; Q9CEE4; -.
DR EnsemblBacteria; AAK05996; AAK05996; L149295.
DR GeneID; 60355972; -.
DR GeneID; 66442903; -.
DR KEGG; lla:L149295; -.
DR PATRIC; fig|272623.7.peg.2033; -.
DR eggNOG; COG1758; Bacteria.
DR HOGENOM; CLU_125406_0_0_9; -.
DR OMA; AHEIDKY; -.
DR Proteomes; UP000002196; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.940.10; -; 1.
DR HAMAP; MF_00366; RNApol_bact_RpoZ; 1.
DR InterPro; IPR003716; DNA-dir_RNA_pol_omega.
DR InterPro; IPR006110; Pol_omega/Rpo6/RPB6.
DR InterPro; IPR036161; RPB6/omega-like_sf.
DR PANTHER; PTHR34476; PTHR34476; 1.
DR Pfam; PF01192; RNA_pol_Rpb6; 1.
DR SMART; SM01409; RNA_pol_Rpb6; 1.
DR SUPFAM; SSF63562; SSF63562; 1.
DR TIGRFAMs; TIGR00690; rpoZ; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW Transcription; Transferase.
FT CHAIN 1..117
FT /note="DNA-directed RNA polymerase subunit omega"
FT /id="PRO_0000128945"
FT REGION 96..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 117 AA; 13434 MW; 6EAD063C8FFE67B7 CRC64;
MMLEPSIDKL LDQVDSKYSL VVLEAKRAHE LRDKERPTKE FKAVKNTLRA LEEIADGTVK
IHPSPELKRE TLVEKRELER LQAKMKEQLI KEQIAKEEAE EEAKQKNSRA AKAAAAE
