ID   RPOZ_STRCO              Reviewed;          90 AA.
AC   Q9KXS1;
DT   04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=DNA-directed RNA polymerase subunit omega;
DE            Short=RNAP omega subunit;
DE            EC=2.7.7.6;
DE   AltName: Full=RNA polymerase omega subunit;
DE   AltName: Full=Transcriptase subunit omega;
GN   Name=rpoZ; OrderedLocusNames=SCO1478; ORFNames=SC9C5.02c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBUNIT.
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=11737643; DOI=10.1046/j.1365-2958.2001.02675.x;
RA   Paget M.S.B., Molle V., Cohen G., Aharonowitz Y., Buttner M.J.;
RT   "Defining the disulphide stress response in Streptomyces coelicolor A3(2):
RT   identification of the sigmaR regulon.";
RL   Mol. Microbiol. 42:1007-1020(2001).
CC   -!- FUNCTION: Promotes RNA polymerase assembly. Latches the N- and C-
CC       terminal regions of the beta' subunit thereby facilitating its
CC       interaction with the beta and alpha subunits (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
CC       {ECO:0000269|PubMed:11737643}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase subunit omega family.
CC       {ECO:0000305}.
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DR   EMBL; AL939109; CAB93358.1; -; Genomic_DNA.
DR   RefSeq; NP_625758.1; NC_003888.3.
DR   RefSeq; WP_003977348.1; NZ_VNID01000021.1.
DR   AlphaFoldDB; Q9KXS1; -.
DR   SMR; Q9KXS1; -.
DR   STRING; 100226.SCO1478; -.
DR   GeneID; 1096904; -.
DR   KEGG; sco:SCO1478; -.
DR   PATRIC; fig|100226.15.peg.1487; -.
DR   eggNOG; COG1758; Bacteria.
DR   HOGENOM; CLU_125406_1_1_11; -.
DR   InParanoid; Q9KXS1; -.
DR   OMA; QHADSKY; -.
DR   PhylomeDB; Q9KXS1; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.940.10; -; 1.
DR   HAMAP; MF_00366; RNApol_bact_RpoZ; 1.
DR   InterPro; IPR003716; DNA-dir_RNA_pol_omega.
DR   InterPro; IPR006110; Pol_omega/Rpo6/RPB6.
DR   InterPro; IPR036161; RPB6/omega-like_sf.
DR   PANTHER; PTHR34476; PTHR34476; 1.
DR   Pfam; PF01192; RNA_pol_Rpb6; 1.
DR   SMART; SM01409; RNA_pol_Rpb6; 1.
DR   SUPFAM; SSF63562; SSF63562; 1.
DR   TIGRFAMs; TIGR00690; rpoZ; 1.
PE   1: Evidence at protein level;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..90
FT                   /note="DNA-directed RNA polymerase subunit omega"
FT                   /id="PRO_0000128990"
SQ   SEQUENCE   90 AA;  9709 MW;  5B5D87917F06A832 CRC64;
     MSSSISAPEG IINPPIDELL EATDSKYSLV IYAAKRARQI NAYYSQLGEG LLEYVGPLVD
     THVHEKPLSI ALREINAGLL TSEAIEGPAQ