AUG7_ARATH
ID AUG7_ARATH Reviewed; 329 AA.
AC Q0WTP1; Q56ZN8; Q8LD35; Q9LF62;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=AUGMIN subunit 7 {ECO:0000303|PubMed:22505726};
GN Name=AUG7 {ECO:0000303|PubMed:22505726};
GN OrderedLocusNames=At5g17620 {ECO:0000312|Araport:AT5G17620};
GN ORFNames=K10A8.100 {ECO:0000312|EMBL:CAC01906.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAE99507.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA de los Reyes C., Quan R., Chen H., Bautista V., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, IDENTIFICATION IN THE AUGMIN COMPLEX BY MASS SPECTROMETRY, AND
RP SUBCELLULAR LOCATION.
RX PubMed=22505726; DOI=10.1105/tpc.112.096610;
RA Hotta T., Kong Z., Ho C.M., Zeng C.J., Horio T., Fong S., Vuong T.,
RA Lee Y.R., Liu B.;
RT "Characterization of the Arabidopsis augmin complex uncovers its critical
RT function in the assembly of the acentrosomal spindle and phragmoplast
RT microtubule arrays.";
RL Plant Cell 24:1494-1509(2012).
CC -!- FUNCTION: Contributes to the assembly of the acentrosomal spindle and
CC phragmoplast microtubule arrays as part of the augmin complex.
CC Regulates the association of gamma-tubulin with the spindle and
CC phragmoplast microtubules. {ECO:0000269|PubMed:22505726}.
CC -!- SUBUNIT: Part of the augmin complex composed of 8 subunits. The complex
CC acts on microtubules and interacts with gamma-tubulin in spindles and
CC the phragmoplast. {ECO:0000269|PubMed:22505726}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000269|PubMed:22505726}. Cytoplasm, cytoskeleton, phragmoplast
CC {ECO:0000269|PubMed:22505726}. Note=Preferentially localizes to
CC microtubules minus ends. {ECO:0000269|PubMed:22505726}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC01906.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL391151; CAC01906.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92449.1; -; Genomic_DNA.
DR EMBL; AK227456; BAE99459.1; -; mRNA.
DR EMBL; AK227507; BAE99507.1; -; mRNA.
DR EMBL; AK220925; BAD94397.1; -; mRNA.
DR EMBL; BT033086; ACF04809.1; -; mRNA.
DR EMBL; AY086231; AAM64307.1; -; mRNA.
DR PIR; T51466; T51466.
DR RefSeq; NP_568354.1; NM_121768.5.
DR AlphaFoldDB; Q0WTP1; -.
DR SMR; Q0WTP1; -.
DR STRING; 3702.AT5G17620.1; -.
DR PaxDb; Q0WTP1; -.
DR PRIDE; Q0WTP1; -.
DR ProteomicsDB; 241013; -.
DR EnsemblPlants; AT5G17620.1; AT5G17620.1; AT5G17620.
DR GeneID; 831628; -.
DR Gramene; AT5G17620.1; AT5G17620.1; AT5G17620.
DR KEGG; ath:AT5G17620; -.
DR Araport; AT5G17620; -.
DR TAIR; locus:2151371; AT5G17620.
DR eggNOG; ENOG502QR4M; Eukaryota.
DR HOGENOM; CLU_073448_0_0_1; -.
DR InParanoid; Q0WTP1; -.
DR OMA; LVEASMY; -.
DR OrthoDB; 880215at2759; -.
DR PhylomeDB; Q0WTP1; -.
DR PRO; PR:Q0WTP1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q0WTP1; baseline and differential.
DR Genevisible; Q0WTP1; AT.
DR GO; GO:0070652; C:HAUS complex; IBA:GO_Central.
DR GO; GO:0009524; C:phragmoplast; IDA:TAIR.
DR GO; GO:0005876; C:spindle microtubule; IDA:TAIR.
DR GO; GO:0051011; F:microtubule minus-end binding; IDA:TAIR.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051225; P:spindle assembly; IBA:GO_Central.
DR InterPro; IPR029711; Haus7-like.
DR InterPro; IPR010604; Plant_AUG7.
DR PANTHER; PTHR14352; PTHR14352; 1.
DR Pfam; PF06694; Plant_NMP1; 1.
DR PIRSF; PIRSF028655; Plant_NMP1; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW Microtubule; Mitosis; Reference proteome.
FT CHAIN 1..329
FT /note="AUGMIN subunit 7"
FT /id="PRO_0000434098"
FT COILED 169..197
FT /evidence="ECO:0000255"
FT CONFLICT 14
FT /note="R -> G (in Ref. 5; AAM64307)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 329 AA; 37009 MW; CAA1602ECAB4DA97 CRC64;
MAAKQMEEIQ KKLRLLSYPR ANAPAQSLLF AGMERYALLE WLFFKLLGDK SPFSQQNLQG
DAGVRDEETV RIQYLAEIAK FLGITPTVDI EAIQGHGTYE DRMEMLRNIV DLVEASLFSD
NQEWSIDEQV AKDIQLIDAI AERQSLIFSE ECKLFPADVQ IQSIYPLPDV SELETKLSEQ
AKILSNLQQK VDDLAAKHAY NPDEEYTEVE SQLRARLESF LETARAFNTI YTKEIRPWTH
MMEVPQLHGF GPAANRLLEA YNMLLKFLGN LKNLRDSHAA LSIGSSGTVA GEPSSVTRIV
SDCEAALTVL NRDLGILSAS IAREQGERL
