ID   RPP14_PONAB             Reviewed;         124 AA.
AC   Q5RB79;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Ribonuclease P protein subunit p14;
GN   Name=RPP14;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of ribonuclease P, a ribonucleoprotein complex that
CC       generates mature tRNA molecules by cleaving their 5'-ends.
CC       {ECO:0000250|UniProtKB:O95059}.
CC   -!- SUBUNIT: RNase P consists of a catalytic RNA moiety and about 10
CC       protein subunits; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30,
CC       RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form
CC       the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form
CC       the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist'
CC       subcomplex. All subunits of the RNase P complex interact with the
CC       catalytic RNA. {ECO:0000250|UniProtKB:O95059}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:O95059}.
CC   -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC       component 2 family. {ECO:0000305}.
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DR   EMBL; CR858774; CAH90981.1; -; mRNA.
DR   RefSeq; NP_001127358.1; NM_001133886.1.
DR   RefSeq; XP_009237129.1; XM_009238854.1.
DR   AlphaFoldDB; Q5RB79; -.
DR   SMR; Q5RB79; -.
DR   STRING; 9601.ENSPPYP00000015396; -.
DR   GeneID; 100174423; -.
DR   KEGG; pon:100174423; -.
DR   CTD; 11102; -.
DR   eggNOG; ENOG502S10S; Eukaryota.
DR   HOGENOM; CLU_157358_0_0_1; -.
DR   InParanoid; Q5RB79; -.
DR   OMA; PCHFQVI; -.
DR   OrthoDB; 1492689at2759; -.
DR   TreeFam; TF324711; -.
DR   Proteomes; UP000001595; Chromosome 3.
DR   GO; GO:0030681; C:multimeric ribonuclease P complex; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0033204; F:ribonuclease P RNA binding; ISS:UniProtKB.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; ISS:UniProtKB.
DR   Gene3D; 3.30.70.3250; -; 1.
DR   InterPro; IPR002759; Pop5/Rpp14/Rnp2-like.
DR   InterPro; IPR038085; Rnp2-like_sf.
DR   Pfam; PF01900; RNase_P_Rpp14; 1.
DR   SUPFAM; SSF160350; SSF160350; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; tRNA processing.
FT   CHAIN           1..124
FT                   /note="Ribonuclease P protein subunit p14"
FT                   /id="PRO_0000140012"
SQ   SEQUENCE   124 AA;  13693 MW;  10AF6C947785DD90 CRC64;
     MPAPAATYER VVYKNPSEYH YMKVCLEFQD CGVGLNAAQF KQLLISAVKD LFGEVDAALP
     LDILTYEEKT LSAILRICSS GLVKLWSSLT LLGSYKGKKC AFRVIQVSPF LLALSGNSRE
     LVLD