ID   RPRMA_DANRE             Reviewed;         103 AA.
AC   Q502I1;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Protein reprimo A {ECO:0000312|ZFIN:ZDB-GENE-050522-218};
GN   Name=rprma {ECO:0000312|ZFIN:ZDB-GENE-050522-218}; ORFNames=zgc:112209;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1] {ECO:0000312|EMBL:AAH95688.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Larva {ECO:0000312|EMBL:AAH95688.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the regulation of p53-dependent G2 arrest
CC       of the cell cycle. {ECO:0000250|UniProtKB:Q9JJ72}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9JJ72,
CC       ECO:0000255}. Membrane {ECO:0000255}; Single-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the reprimo family. {ECO:0000255}.
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DR   EMBL; BC095688; AAH95688.1; -; mRNA.
DR   RefSeq; NP_001018500.1; NM_001020664.1.
DR   AlphaFoldDB; Q502I1; -.
DR   STRING; 7955.ENSDARP00000069903; -.
DR   PaxDb; Q502I1; -.
DR   Ensembl; ENSDART00000075420; ENSDARP00000069903; ENSDARG00000053383.
DR   GeneID; 553689; -.
DR   KEGG; dre:553689; -.
DR   CTD; 553689; -.
DR   ZFIN; ZDB-GENE-050522-218; rprma.
DR   eggNOG; ENOG502S262; Eukaryota.
DR   GeneTree; ENSGT00390000010523; -.
DR   HOGENOM; CLU_170456_0_0_1; -.
DR   InParanoid; Q502I1; -.
DR   OMA; ERNLFIM; -.
DR   OrthoDB; 1529294at2759; -.
DR   PhylomeDB; Q502I1; -.
DR   TreeFam; TF332720; -.
DR   PRO; PR:Q502I1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 9.
DR   Bgee; ENSDARG00000053383; Expressed in vasculature of brain and 35 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:InterPro.
DR   InterPro; IPR033356; Reprimo.
DR   InterPro; IPR043383; Reprimo_fam.
DR   PANTHER; PTHR28649; PTHR28649; 1.
DR   PANTHER; PTHR28649:SF2; PTHR28649:SF2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..103
FT                   /note="Protein reprimo A"
FT                   /id="PRO_0000392920"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   103 AA;  11323 MW;  E10EDCE2B2AFCA40 CRC64;
     MNSTFNQTDS GIFSNRTEEN LLCCNFSSVV TDNGFAAAAP DERSLFIMRI VQIAVMCVLS
     LTVVFGIFFL GCNLLIKSEG MINFLVTDRR PSKEVEAVIV GAY