RPRMB_DANRE
ID RPRMB_DANRE Reviewed; 102 AA.
AC Q6PBK8;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Protein reprimo B;
GN Name=rprmb; Synonyms=rprm; ORFNames=zgc:73361;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Retina;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the regulation of p53-dependent G2 arrest
CC of the cell cycle. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000305};
CC Single-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the reprimo family. {ECO:0000305}.
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DR EMBL; BC059672; AAH59672.1; -; mRNA.
DR RefSeq; NP_957100.1; NM_200806.1.
DR AlphaFoldDB; Q6PBK8; -.
DR STRING; 7955.ENSDARP00000033402; -.
DR PaxDb; Q6PBK8; -.
DR Ensembl; ENSDART00000038505; ENSDARP00000033402; ENSDARG00000024006.
DR GeneID; 393779; -.
DR KEGG; dre:393779; -.
DR CTD; 393779; -.
DR ZFIN; ZDB-GENE-040426-1779; rprmb.
DR eggNOG; ENOG502S262; Eukaryota.
DR GeneTree; ENSGT00390000010523; -.
DR HOGENOM; CLU_170456_0_0_1; -.
DR InParanoid; Q6PBK8; -.
DR OMA; ERSVFIM; -.
DR OrthoDB; 1529294at2759; -.
DR PhylomeDB; Q6PBK8; -.
DR TreeFam; TF332720; -.
DR PRO; PR:Q6PBK8; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 6.
DR Bgee; ENSDARG00000024006; Expressed in vasculature of brain and 39 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:InterPro.
DR InterPro; IPR033356; Reprimo.
DR InterPro; IPR043383; Reprimo_fam.
DR PANTHER; PTHR28649; PTHR28649; 1.
DR PANTHER; PTHR28649:SF2; PTHR28649:SF2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..102
FT /note="Protein reprimo B"
FT /id="PRO_0000312755"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 102 AA; 11006 MW; 3D069FE8324BA6DA CRC64;
MNSTGFNDTD SALFSNTSFL SCCNVSSVVT DSGFVSAALD ERSVFIMRTV QIAVMCVLAL
TVVFGIFFLG CNLLIKSEGM INFLVTDRRP SKDVEAVIVG SY