ID   RPRY_BACFR              Reviewed;         236 AA.
AC   Q9AE24; Q64PH5; Q9R5Z7;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 2.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Transcriptional regulatory protein RprY;
GN   Name=rprY; OrderedLocusNames=BF3864;
OS   Bacteroides fragilis (strain YCH46).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=295405;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8469117; DOI=10.1111/j.1365-2958.1993.tb01167.x;
RA   Rasmussen B.A., Kovacs E.;
RT   "Cloning and identification of a two-component signal-transducing
RT   regulatory system from Bacteroides fragilis.";
RL   Mol. Microbiol. 7:765-776(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YCH46;
RX   PubMed=15466707; DOI=10.1073/pnas.0404172101;
RA   Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N.,
RA   Kuhara S., Hattori M., Hayashi T., Ohnishi Y.;
RT   "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions
RT   regulating cell surface adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004).
CC   -!- FUNCTION: Member of the two-component regulatory system RprX/RprY.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Phosphorylated by RprX. {ECO:0000305}.
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DR   EMBL; S59000; AAK14820.1; -; Genomic_DNA.
DR   EMBL; AP006841; BAD50606.1; -; Genomic_DNA.
DR   PIR; S33662; S33662.
DR   RefSeq; YP_101140.1; NC_006347.1.
DR   AlphaFoldDB; Q9AE24; -.
DR   SMR; Q9AE24; -.
DR   STRING; 295405.BF3864; -.
DR   PRIDE; Q9AE24; -.
DR   EnsemblBacteria; BAD50606; BAD50606; BF3864.
DR   KEGG; bfr:BF3864; -.
DR   PATRIC; fig|295405.11.peg.3709; -.
DR   HOGENOM; CLU_000445_30_3_10; -.
DR   OMA; NIHGEGF; -.
DR   Proteomes; UP000002197; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00448; REC; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..236
FT                   /note="Transcriptional regulatory protein RprY"
FT                   /id="PRO_0000081220"
FT   DOMAIN          9..123
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        134..231
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT   MOD_RES         58
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   CONFLICT        136
FT                   /note="V -> I (in Ref. 1; AAK14820)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   236 AA;  27177 MW;  B4899BF53334454B CRC64;
     MIDMDEKLRI LLCEDDENLG MLLREYLQAK GYSAELYPDG EAGFKAFLKN KYDLCVFDVM
     MPKKDGFTLA QEVRAANAEI PIIFLTAKTL KEDILEGFKI GADDYITKPF SMEELTFRIE
     AILRRVRGKK NKESNVYKIG KFTFDTQKQI LAIGDKQTKL TTKESELLGL LCAHANEILQ
     RDFALKTIWI DDNYFNARSM DVYITKLRKH LKDDDSIEII NIHGKGYKLI TPEPES