ID   RPSB_BACAN              Reviewed;         257 AA.
AC   Q9K5J6; Q6I2H8; Q6KWA6;
DT   24-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 131.
DE   RecName: Full=RNA polymerase sigma-B factor;
GN   Name=sigB; OrderedLocusNames=BA_0992, GBAA_0992, BAS0928;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=9131;
RX   PubMed=10960085; DOI=10.1128/jb.182.18.5036-5045.2000;
RA   Fouet A., Namy O., Lambert G.;
RT   "Characterization of the operon encoding the alternative sigma(B) factor
RT   from Bacillus anthracis and its role in virulence.";
RL   J. Bacteriol. 182:5036-5045(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. SigB subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAT53253.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ272497; CAB95034.1; -; Genomic_DNA.
DR   EMBL; AE016879; AAP24979.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT30095.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT53253.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_843493.1; NC_003997.3.
DR   RefSeq; YP_027202.1; NC_005945.1.
DR   AlphaFoldDB; Q9K5J6; -.
DR   SMR; Q9K5J6; -.
DR   STRING; 261594.GBAA_0992; -.
DR   DNASU; 1088960; -.
DR   EnsemblBacteria; AAP24979; AAP24979; BA_0992.
DR   EnsemblBacteria; AAT30095; AAT30095; GBAA_0992.
DR   KEGG; ban:BA_0992; -.
DR   KEGG; bar:GBAA_0992; -.
DR   KEGG; bat:BAS0928; -.
DR   PATRIC; fig|1392.230.peg.975; -.
DR   eggNOG; COG1191; Bacteria.
DR   HOGENOM; CLU_014793_8_5_9; -.
DR   OMA; FIRDKTW; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IMP:TIGR.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IMP:TIGR.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014288; RNA_pol_sigma-B.
DR   InterPro; IPR014322; RNA_pol_sigma-B/F/G.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02980; SigBFG; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   TIGRFAMs; TIGR02941; Sigma_B; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Sigma factor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..257
FT                   /note="RNA polymerase sigma-B factor"
FT                   /id="PRO_0000093938"
FT   DNA_BIND        224..243
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           58..71
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   257 AA;  29301 MW;  B8DF57DCA13B7731 CRC64;
     MEIQSQPTNL TKEDVIKLIA EFQQNQCGEA QERLVDHYKN LVYSIAYRYS KGGPMHEDII
     QVGMLGLLGA IRRYDYSIGN AFEPFAIPTI VGEIKKYLRD KTWGIHVPRR IKDLGGKIKL
     AIEELTDHLQ RSPKIIEIAD HLGLSEEEVL EIMDAKNNYR VSSLDDVVEN ASDGSSVARI
     ESVGEVEQGY EQTERRLVLK DIFNVLNETE KSVIHYIFEE NLNQKDTGER LGISQMHVSR
     IKRQAISKLK QAAFLDT