ID   RPSC_MYXXA              Reviewed;         295 AA.
AC   Q07083;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=RNA polymerase sigma-C factor;
GN   Name=sigC;
OS   Myxococcus xanthus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=34;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FB / DZF1;
RX   PubMed=8501037; DOI=10.1128/jb.175.11.3335-3342.1993;
RA   Apelian D., Inouye S.;
RT   "A new putative sigma factor of Myxococcus xanthus.";
RL   J. Bacteriol. 175:3335-3342(1993).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is essential for normal fruiting body
CC       formation.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. {ECO:0000305}.
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DR   EMBL; L12992; AAA25408.1; -; Genomic_DNA.
DR   PIR; A40587; A40587.
DR   RefSeq; WP_011556153.1; NZ_JABFNQ010000054.1.
DR   AlphaFoldDB; Q07083; -.
DR   SMR; Q07083; -.
DR   GeneID; 41363437; -.
DR   OMA; HEQLGRW; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Sigma factor; Transcription; Transcription regulation.
FT   CHAIN           1..295
FT                   /note="RNA polymerase sigma-C factor"
FT                   /id="PRO_0000093968"
FT   DNA_BIND        250..269
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           73..86
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   295 AA;  33433 MW;  DB2D4E7832C7FA49 CRC64;
     MQASNSFSSP DSLSTYLSEI NQYPLLTQPQ EQELSKRFRA GDLAAGHQLV TANLRFVVKV
     AYEYRSYGLK MSDLIQEANI GLMKAVQKFD PDKGIRLISY AVWWIRAYIQ NCILKNWSLV
     KLGTTQAQRR LFFSLARTRR ELEKMGAGDA NVVNAEEIAR KLNVKASEVR EMEQRMGGRD
     LSLDAPMGED GDATHLDFVE SESVSAVDEV ADRQQANLTR ELVQRALRRL DPRERFIIEQ
     RVMGDAEMTL SELGEHFGFS RERARQLEIR AKDKLKLALV TLMAEAGVDE STLNA