ID   RPSC_SYNY3              Reviewed;         404 AA.
AC   Q59996;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 135.
DE   RecName: Full=Probable RNA polymerase sigma-C factor;
GN   Name=sigC; OrderedLocusNames=sll0184;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27184 / PCC 6803 / N-1;
RX   PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA   Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA   Sugiura M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT   from map positions 64% to 92% of the genome.";
RL   DNA Res. 2:153-166(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA10419.1; -; Genomic_DNA.
DR   PIR; S76573; S76573.
DR   AlphaFoldDB; Q59996; -.
DR   SMR; Q59996; -.
DR   IntAct; Q59996; 13.
DR   STRING; 1148.1001684; -.
DR   PaxDb; Q59996; -.
DR   EnsemblBacteria; BAA10419; BAA10419; BAA10419.
DR   KEGG; syn:sll0184; -.
DR   eggNOG; COG0568; Bacteria.
DR   InParanoid; Q59996; -.
DR   OMA; KKYQQRG; -.
DR   PhylomeDB; Q59996; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR017848; RNA_pol_sigma_RpoD_cyanobac.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02997; Sig70-cyanoRpoD; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Sigma factor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..404
FT                   /note="Probable RNA polymerase sigma-C factor"
FT                   /id="PRO_0000093937"
FT   DNA_BIND        362..381
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           193..206
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   404 AA;  46581 MW;  CDCBE67BF031D0F9 CRC64;
     MTKPSNDEPP LTNVRDLEAM LPLEEEDLTA DSQDLEYTAV AHRQQFSTDL VRLYLQDIGR
     IPLLKRDEEV HIAQQVQSYL RLVEIQNRAA ESDAAIDQYQ TAIAVHDQLL VQLGHRPSYE
     RWAKILGQTV ATLKQTLKSG KKRWAELAGL TVEELENIEK QGITAKAHMI KANLRLVVSV
     AKKYQNRGLE LLDLIQEGTL GLERAVEKFD PTKGYRFSTY SYWWIRQGIT RAIATQSRMI
     RLPVHITEKL NKIKRAQRKI SQEKGHTPKI DEVAEELGMT PEQVREVLTQ VPRSVSLELK
     VGQDKDTELM DLLETDTQSP EDELMREALQ NDMQEILLDL TPREQEVIAL RFGFQDGVAH
     SLSEIGRILN LSRERVRQIE AKALQKLRHP RRRDRIRDYY ENLG