RPSF_BACLI
ID RPSF_BACLI Reviewed; 255 AA.
AC P26764;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=RNA polymerase sigma-F factor;
DE AltName: Full=Sporulation sigma factor;
DE AltName: Full=Stage II sporulation protein AC;
GN Name=sigF; Synonyms=spoIIAC;
OS Bacillus licheniformis.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1402;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 9789 / DSM 8785 / NBRC 12195 / NCIMB 6346 / NCTC 6346 / IMET
RC 11025 / NRS 243;
RX PubMed=2513372; DOI=10.1099/00221287-135-4-767;
RA Yudkin M.D., Appleby L., Smith A.J.;
RT "Nucleotide sequence of the Bacillus licheniformis homologue of the
RT sporulation locus spoIIA of Bacillus subtilis.";
RL J. Gen. Microbiol. 135:767-775(1989).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. This sigma factor is responsible for the expression of
CC sporulation specific genes.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. {ECO:0000305}.
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DR EMBL; M25260; AAA22797.1; -; Genomic_DNA.
DR PIR; C37165; C37165.
DR AlphaFoldDB; P26764; -.
DR SMR; P26764; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 2.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR014322; RNA_pol_sigma-B/F/G.
DR InterPro; IPR014236; RNA_pol_sigma-F.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88659; SSF88659; 2.
DR SUPFAM; SSF88946; SSF88946; 1.
DR TIGRFAMs; TIGR02980; SigBFG; 1.
DR TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR TIGRFAMs; TIGR02885; spore_sigF; 1.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Sigma factor; Sporulation; Transcription;
KW Transcription regulation.
FT CHAIN 1..255
FT /note="RNA polymerase sigma-F factor"
FT /id="PRO_0000093944"
FT DNA_BIND 221..240
FT /note="H-T-H motif"
FT /evidence="ECO:0000250"
FT MOTIF 61..74
FT /note="Polymerase core binding"
SQ SEQUENCE 255 AA; 29642 MW; B3FD4708914A299B CRC64;
MDVEVKKENQ NTQLKDHEVK ELIKNSQNGD QKARDLLIEK NMRLVWSVVQ RFLNRGYEPD
DLFQIGCIGL LKSVDKFDLS YDVRFSTYAV PMIIGEIQRF IRDDGTVKVS RSLKELGNKI
RRAKEELSKS NGRIPTVQEI ADYLEISSEE VVMAQEAVRS PSSIHETVYE NDGDPITLLD
QIADQSEEKW FDKIALKEAI KDLDEREKLI VYLRYYKDKT QSEVADRLGI SQVQVSRLEK
KILKQIKNQM DHFES