ID   RPSG_CLOAB              Reviewed;         257 AA.
AC   P33658;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   25-MAY-2022, entry version 136.
DE   RecName: Full=RNA polymerase sigma-G factor;
GN   Name=sigG; OrderedLocusNames=CA_C1696;
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=7961408; DOI=10.1128/jb.176.21.6572-6582.1994;
RA   Sauer U., Treuner A., Buchholz M., Santangelo J.D., Durre P.;
RT   "Sporulation and primary sigma factor homologous genes in Clostridium
RT   acetobutylicum.";
RL   J. Bacteriol. 176:6572-6582(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=7883192; DOI=10.1016/0378-1119(94)00818-d;
RA   Wong J., Sass C., Bennett G.N.;
RT   "Sequence and arrangement of genes encoding sigma factors in Clostridium
RT   acetobutylicum ATCC 824.";
RL   Gene 153:89-92(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA   Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is responsible for the expression of
CC       sporulation specific genes.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. {ECO:0000305}.
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DR   EMBL; Z23079; CAA80621.1; -; Genomic_DNA.
DR   EMBL; U07420; AAC43310.1; -; Genomic_DNA.
DR   EMBL; AE001437; AAK79662.1; -; Genomic_DNA.
DR   PIR; C97109; C97109.
DR   PIR; I40621; I40621.
DR   RefSeq; NP_348322.1; NC_003030.1.
DR   RefSeq; WP_010965003.1; NC_003030.1.
DR   AlphaFoldDB; P33658; -.
DR   SMR; P33658; -.
DR   STRING; 272562.CA_C1696; -.
DR   EnsemblBacteria; AAK79662; AAK79662; CA_C1696.
DR   GeneID; 44998191; -.
DR   KEGG; cac:CA_C1696; -.
DR   PATRIC; fig|272562.8.peg.1899; -.
DR   eggNOG; COG1191; Bacteria.
DR   HOGENOM; CLU_014793_8_5_9; -.
DR   OMA; CGVNTAK; -.
DR   OrthoDB; 1565734at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014322; RNA_pol_sigma-B/F/G.
DR   InterPro; IPR014212; RNA_pol_sigma-G.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02980; SigBFG; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   TIGRFAMs; TIGR02850; spore_sigG; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Sigma factor; Sporulation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..257
FT                   /note="RNA polymerase sigma-G factor"
FT                   /id="PRO_0000093946"
FT   DNA_BIND        228..247
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           66..79
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   257 AA;  29656 MW;  A877CD3486B45FBE CRC64;
     MVINKVEICG VNTSKLPVLK EKEMRELLIS MRNGNTTARE KFIKGNLRLV LSVIQRFNNR
     GENADDLFQV GCIGLIKSID NFDLSQNVKF STYAVPMIIG EIRRYLRDNN SIRVSRSLRD
     IAYRALQVRD RLISKNNKEP TVSQIAKELK IPREEVIFAL DAIQDPISLF EPIYHDDGDA
     IYVMDQISDN KNLDDSWLQN ISIKEAMKKL SDREKMILNM RFFDGRTQME VADEIGISQA
     QVSRLEKTAL KHMKKYV