ID   RPSH_BACLI              Reviewed;         223 AA.
AC   P02964; P11702;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=RNA polymerase sigma-H factor;
DE   AltName: Full=Sigma-30;
GN   Name=sigH; Synonyms=spo0H;
OS   Bacillus licheniformis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1402;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3277943; DOI=10.1128/jb.170.3.1054-1062.1988;
RA   Dubnau E., Weir J., Nair G., Carter L. III, Moran C.P. Jr., Smith I.;
RT   "Bacillus sporulation gene spo0H codes for sigma 30 (sigma H).";
RL   J. Bacteriol. 170:1054-1062(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FD02;
RX   PubMed=6322121; DOI=10.1093/nar/12.4.1779;
RA   Ramakrishna N., Dubnau E., Smith I.;
RT   "The complete DNA sequence and regulatory regions of the Bacillus
RT   licheniformis spoOH gene.";
RL   Nucleic Acids Res. 12:1779-1790(1984).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor is involved in the transition to post-
CC       exponential phase in the beginning of sporulation.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA25119.1; Type=Miscellaneous discrepancy; Evidence={ECO:0000305};
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DR   EMBL; M29694; AAA22755.1; -; Genomic_DNA.
DR   EMBL; X00413; CAA25119.1; ALT_SEQ; Genomic_DNA.
DR   PIR; B28625; SZBSSL.
DR   RefSeq; WP_003178288.1; NZ_VTQZ01000021.1.
DR   AlphaFoldDB; P02964; -.
DR   SMR; P02964; -.
DR   GeneID; 56669811; -.
DR   GeneID; 66217738; -.
DR   PATRIC; fig|1402.62.peg.2010; -.
DR   OMA; LEWKVLM; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014218; RNA_pol_sigma-H.
DR   InterPro; IPR016371; RNA_pol_sigma-H_factor.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   PIRSF; PIRSF002939; RNA_polymerase_sigma-H_factor; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   TIGRFAMs; TIGR02859; spore_sigH; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Sigma factor; Sporulation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..223
FT                   /note="RNA polymerase sigma-H factor"
FT                   /id="PRO_0000093948"
FT   DNA_BIND        187..206
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           67..80
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   223 AA;  26109 MW;  C50BFB12D67EB504 CRC64;
     MNLQNNQGKF SKEQFSKERF CQLEDEQVIE MVHVGDSDAL DYLITKYRNF VRAKARSYFL
     IGADREDIVQ EGMIGLYKSI RDFREDKLTS FKAFAELCIT RQIITAIKTA TRQKHIPLNS
     YVSLDKPIYD EESDRTLLDV ISGAKVMNPE ELIINQEEFD DIELKMGELL SDLERKVLAL
     YLDGRSYQEI SEELNRHVKS IDNALQRVKR KLEKYLELRE ISL