AUR51_RANAE
ID AUR51_RANAE Reviewed; 25 AA.
AC P69029; P82401;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 23.
DE RecName: Full=Aurein-5.1;
OS Ranoidea aurea (Green and golden bell frog) (Litoria aurea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Pelodryadinae; Ranoidea.
OX NCBI_TaxID=8371;
RN [1]
RP PROTEIN SEQUENCE, AND FUNCTION.
RC TISSUE=Skin secretion;
RX PubMed=10951191; DOI=10.1046/j.1432-1327.2000.01536.x;
RA Rozek T., Wegener K.L., Bowie J.H., Olver I.N., Carver J.A., Wallace J.C.,
RA Tyler M.J.;
RT "The antibiotic and anticancer active aurein peptides from the australian
RT bell frogs Litoria aurea and Litoria raniformis the solution structure of
RT aurein 1.2.";
RL Eur. J. Biochem. 267:5330-5341(2000).
CC -!- FUNCTION: Has no antimicrobial or anticancer activity.
CC {ECO:0000269|PubMed:10951191}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the skin dorsal glands.
CC -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC Aurein subfamily. {ECO:0000305}.
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DR AlphaFoldDB; P69029; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR InterPro; IPR032021; Frog_Litoria.
DR Pfam; PF16049; Antimicrobial24; 1.
PE 1: Evidence at protein level;
KW Amphibian defense peptide; Direct protein sequencing; Secreted.
FT PEPTIDE 1..25
FT /note="Aurein-5.1"
FT /id="PRO_0000043733"
SQ SEQUENCE 25 AA; 2547 MW; 15C6169CD98AFC27 CRC64;
GLLDIVTGLL GNLIVDVLKP KTPAS