AB53G_ORYSJ
ID AB53G_ORYSJ Reviewed; 1446 AA.
AC A3BXL8; C7J764; Q6EQ63; Q6EQ64;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=ABC transporter G family member 53 {ECO:0000305};
DE Short=OsABCG53 {ECO:0000305};
DE AltName: Full=Pleiotropic drug resistance protein 20 {ECO:0000303|PubMed:16506311};
DE Short=OsPDR20 {ECO:0000303|PubMed:16506311};
GN Name=ABCG53 {ECO:0000305}; Synonyms=PDR20 {ECO:0000303|PubMed:16506311};
GN OrderedLocusNames=Os09g0332700 {ECO:0000312|EMBL:BAH94511.1},
GN LOC_Os09g16330;
GN ORFNames=OsJ_28928 {ECO:0000312|EMBL:EAZ44307.1},
GN OSJNBa0017I18.21 {ECO:0000312|EMBL:BAD29206.1,
GN ECO:0000312|EMBL:BAD29207.1},
GN OSJNBb0095I04.27 {ECO:0000312|EMBL:BAD29138.1,
GN ECO:0000312|EMBL:BAD29139.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare; TISSUE=Root {ECO:0000312|EMBL:ACD31691.1};
RA Moons A.;
RT "Transcriptional profiling of the PDR gene family in rice roots in response
RT to plant growth regulators, redox perturbations and weak organic acid
RT stress.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1000-1446.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16506311; DOI=10.1016/j.febslet.2005.12.043;
RA Crouzet J., Trombik T., Fraysse A.S., Boutry M.;
RT "Organization and function of the plant pleiotropic drug resistance ABC
RT transporter family.";
RL FEBS Lett. 580:1123-1130(2006).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: May be a general defense protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD29138.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD29139.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD29206.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD29207.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAG87376.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAH94511.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP005701; BAD29138.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005701; BAD29139.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005724; BAD29206.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005724; BAD29207.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008215; BAH94511.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014965; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000146; EAZ44307.1; -; Genomic_DNA.
DR EMBL; EU682752; ACD31691.1; -; mRNA.
DR EMBL; AK060237; BAG87376.1; ALT_INIT; mRNA.
DR RefSeq; XP_015611955.1; XM_015756469.1.
DR AlphaFoldDB; A3BXL8; -.
DR SMR; A3BXL8; -.
DR STRING; 4530.OS09T0332700-01; -.
DR PaxDb; A3BXL8; -.
DR PRIDE; A3BXL8; -.
DR GeneID; 9269190; -.
DR KEGG; osa:9269190; -.
DR eggNOG; KOG0065; Eukaryota.
DR OrthoDB; 324553at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1446
FT /note="ABC transporter G family member 53"
FT /id="PRO_0000433462"
FT TRANSMEM 523..543
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 610..630
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 641..661
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 666..686
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 752..772
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1195..1215
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1225..1242
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1281..1301
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1308..1328
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1338..1358
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1363..1383
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1415..1435
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 153..426
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 504..717
FT /note="ABC transmembrane type-2 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
FT DOMAIN 849..1101
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1174..1388
FT /note="ABC transmembrane type-2 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
FT BINDING 186..193
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 894..901
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 1016
FT /note="V -> A (in Ref. 6; BAG87376)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1446 AA; 162765 MW; A768B16A434F7DC5 CRC64;
MDDAGEIHAL GGSLRREASS ARSGDAAVFF SRSSSRDEDD EEALRWAALE KLPTYDRART
AVLAMPEGEL REVNVQRLGP QERHALLQRL AWVGDDHARF LSKFKDRVDR VGIELPTIEV
RYENLNVEAE AYVGSRGLPT ILNTYANVLE GLANTLHITP NRKQKISILH NVSGIIKPHR
MTLLLGPPGA GKTTLLLALA GNVPSGLKVS GQITYNGHTM DEFEPRRSAA YVSQHDLHMG
ELTVRETVNF SAKCQGIGHR YDLLMELSRR EKEENIKPDP EVDIYLKAAA TGEQKAEVVT
NHILKVLGLD ICADTIVGNN MLRGISGGQK KRVTTAEMIV TPGRALFMDE ISTGLDSSTT
YNIVDSIRQT IHIVGGTAVI ALLQPAPETY ELFDDIILLS DGQVVYNGPR EHVLEFFESV
GFKCPERKGV ADFLQEVTSR KDQRQYWMHG DETYRYVPVK EFAEAFQSFH VGQAIRSELA
IPFDKSRSHP AALKTSKYGA SMKELLKANI DREILLMKRN SFVYIFKATQ LTLMTFIAMT
VFIRTNMHHD SITNGGIYMG ALFFGILMIM FNGLAEVGLT IAKLPVFFKQ RDLLFYPAWT
YSLPSWIIKT PLSLLNVTIW VFITYYVIGF DPNVERLFRQ FLLLLVMNET SSGLFRFIAG
FARHQVVAST MGSFCILIFM LLGGFILSRE NVKKWWIWGY WISPLMYAQN AISVNEFLGH
SWNKTIPGFR EPLGKLVLES RGVFPEAKWY WIGVGALLGY VLLFNILYTI CLTFLNPFDS
NQPTISEETL KIKQANLTGD VIEASSRGRI TTNTNTADDS NDEAISNHAT VNSSPGKKGM
VLPFVPLSIT FEDIRYSVDM PEVIKAQGVT ESRLELLKGI SGSFRPGVLT ALMGVSGAGK
TTLMDVLAGR KTSGYIEGNI TISGYPKKQE TFARVSGYCE QNDIHSPNVT VYESLAFSAW
LRLPAEIDSA TRKMFIDEVM ELVELSPLKD SLVGLPGVSG LSTEQRKRLT IAVELVANPS
IIFMDEPTSG LDARAAAIVM RAIRNTVDTG RTVVCTIHQP SIDIFESFDE LFLMKRGGEE
IYVGPVGQHS CELIRYFESI EGVSKIKHGY NPSTWMLEVT STVQEQITGV NFSEIYKNSE
LYRRNKSMIK ELSSPPDGSS DLSFPTEYSQ TFITQCLACL WKQSLSYWRN PPYTAVKYFY
TIVIALLFGT MFWGVGRKRS NQQDLFNAMG SMYASVLFMG VQNSSSVQPV VSVERTVFYR
ERAAHMYSPL PYALGQVAIE LPYILVQSLI YGVLVYAMIG FEWTAAKFFW YLFFMYFTLS
YYTFYGMMSV GLTPSYNVAS VVSTAFYAIW NLFSGFIIPR TRIPIWWRWY YWVCPVAWTL
YGLVTSQFGD VTDTFDNGVR ISDFVESYFG YHRDFLWVVA VMVVSFAVLF AFLFGLSIKI
FNFQKR
