AB5F_ARATH
ID AB5F_ARATH Reviewed; 692 AA.
AC Q9LV93; Q93ZN6;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=ABC transporter F family member 5;
DE Short=ABC transporter ABCF.5;
DE Short=AtABCF5;
DE AltName: Full=GCN20-type ATP-binding cassette protein GCN5;
GN Name=ABCF5; Synonyms=GCN5; OrderedLocusNames=At5g64840; ORFNames=MXK3.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [6]
RP GENE FAMILY.
RX PubMed=11855639; DOI=10.1007/s004250100661;
RA Martinoia E., Klein M., Geisler M., Bovet L., Forestier C.,
RA Kolukisaoglu H.U., Mueller-Roeber B., Schulz B.;
RT "Multifunctionality of plant ABC transporters -- more than just
RT detoxifiers.";
RL Planta 214:345-355(2002).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC EF3 (TC 3.A.1.121) subfamily. {ECO:0000305}.
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DR EMBL; AB019236; BAA97296.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97960.1; -; Genomic_DNA.
DR EMBL; AY056435; AAL08291.1; -; mRNA.
DR EMBL; BT000510; AAN18079.1; -; mRNA.
DR EMBL; AK227200; BAE99239.1; -; mRNA.
DR RefSeq; NP_201289.1; NM_125882.3.
DR AlphaFoldDB; Q9LV93; -.
DR SMR; Q9LV93; -.
DR BioGRID; 21849; 1.
DR STRING; 3702.AT5G64840.1; -.
DR PaxDb; Q9LV93; -.
DR PRIDE; Q9LV93; -.
DR ProteomicsDB; 244556; -.
DR EnsemblPlants; AT5G64840.1; AT5G64840.1; AT5G64840.
DR GeneID; 836607; -.
DR Gramene; AT5G64840.1; AT5G64840.1; AT5G64840.
DR KEGG; ath:AT5G64840; -.
DR Araport; AT5G64840; -.
DR TAIR; locus:2177689; AT5G64840.
DR eggNOG; KOG0927; Eukaryota.
DR HOGENOM; CLU_000604_36_0_1; -.
DR InParanoid; Q9LV93; -.
DR OMA; AQADKMR; -.
DR OrthoDB; 580544at2759; -.
DR PhylomeDB; Q9LV93; -.
DR PRO; PR:Q9LV93; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LV93; baseline and differential.
DR Genevisible; Q9LV93; AT.
DR GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0009624; P:response to nematode; HEP:TAIR.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR032781; ABC_tran_Xtn.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF12848; ABC_tran_Xtn; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 2: Evidence at transcript level;
KW ATP-binding; Nucleotide-binding; Reference proteome; Repeat; Transport.
FT CHAIN 1..692
FT /note="ABC transporter F family member 5"
FT /id="PRO_0000379142"
FT DOMAIN 98..356
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 425..640
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT REGION 64..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..672
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 130..137
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 457..464
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 82
FT /note="R -> Q (in Ref. 3; AAN18079/AAL08291)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 692 AA; 78001 MW; DE182E92D4383000 CRC64;
MGLSTNLHSL DLRSTFFTGL RTSPIPSNFI KISSISNPRR DISTIRAQVS TISLETSVKQ
RQDEIESLFS KQPSQQDSDR KRNGKSSKNG ASGISSGVKL ENIRKSYKGV TVLKDVTWEV
KRGEKVGLVG VNGAGKTTQL RIITGQEEPD SGNVIKAKPN MKVAFLSQEF EVSMSKTVRE
EFMTAFKEEM EITEKLEKVQ KAIEGSVDDL DLMGRLLDEF DLLQRRAQAV NLDSVDAKIS
KLMPELGFAP EDADRLVASF SGGWQMRMSL GKILLQDPDL LLLDEPTNHL DLDTIEWLEG
YLQKQDVPMV IISHDRAFLD QLCTKIVETE MGVSRTFEGN YSQYVISKAE WIETQNAAWE
KQQKDIDSTK DLIARLGAGA NSGRASTAEK KLEKLQEQEL IEKPFQRKQM KIRFPERGTS
GRSVVNVKNI DFGFEDKMLF KKANLSIERG EKIAILGPNG CGKSTLLKLI MGLEKPVKGE
VILGEHNVLP NYFEQNQAEV LDLDKTVLET VCEAAEDWRS DDIKGLLGRC NFKADMLDRK
VSLLSGGEKA RLAFCKFMVT PSTLLVLDEP TNHLDIPSKE MLEEAINEYQ GTVIAVSHDR
YFIKQIVNRV IEVEDGCLED YAGDYNYYLE KNLDARTKEL EREAELEEKA PKVKAKSKMS
KAEKEARKKQ KMQAFQQAKQ KSKASKNSKR WN
