ID   AUX22_SOYBN             Reviewed;         195 AA.
AC   P13088;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Auxin-induced protein AUX22;
GN   Name=AUX22;
OS   Glycine max (Soybean) (Glycine hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3847;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Corsoy;
RX   PubMed=2899079; DOI=10.1016/s0021-9258(18)38022-0;
RA   Ainley W.M., Walker J.C., Nagao R.T., Key J.L.;
RT   "Sequence and characterization of two auxin-regulated genes from soybean.";
RL   J. Biol. Chem. 263:10658-10666(1988).
CC   -!- FUNCTION: Aux/IAA proteins are short-lived transcriptional factors that
CC       function as repressors of early auxin response genes at low auxin
CC       concentrations. Repression is thought to result from the interaction
CC       with auxin response factors (ARFs), proteins that bind to the auxin-
CC       responsive promoter element (AuxRE). Formation of heterodimers with ARF
CC       proteins may alter their ability to modulate early auxin response genes
CC       expression (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimers and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- INDUCTION: By auxin.
CC   -!- DOMAIN: The N-terminal half of the protein contains two conserved
CC       domains I and II. Domain I includes a slightly degenerated ERF-
CC       associated amphiphilic repression (EAR) motif which seems to be
CC       involved in the activity of transcriptional repression. Domain II is
CC       required for the correct degradation of the protein through the SCF-
CC       mediated ubiquitin-proteasome pathway. Interactions between Aux/IAA
CC       proteins and auxin response factors (ARFs) occur through their C-
CC       terminal dimerization domains III and IV (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Aux/IAA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; J03920; AAA33944.1; -; mRNA.
DR   PIR; B28993; B28993.
DR   RefSeq; NP_001237849.1; NM_001250920.1.
DR   AlphaFoldDB; P13088; -.
DR   SMR; P13088; -.
DR   STRING; 3847.GLYMA08G22190.1; -.
DR   PRIDE; P13088; -.
DR   EnsemblPlants; KRH44390; KRH44390; GLYMA_08G207900.
DR   GeneID; 547784; -.
DR   Gramene; KRH44390; KRH44390; GLYMA_08G207900.
DR   KEGG; gmx:547784; -.
DR   eggNOG; ENOG502RXTN; Eukaryota.
DR   HOGENOM; CLU_049393_0_1_1; -.
DR   InParanoid; P13088; -.
DR   OMA; DICDEAN; -.
DR   OrthoDB; 1208467at2759; -.
DR   Proteomes; UP000008827; Chromosome 8.
DR   Genevisible; P13088; GM.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR033389; AUX/IAA_dom.
DR   InterPro; IPR003311; AUX_IAA.
DR   InterPro; IPR000270; PB1_dom.
DR   PANTHER; PTHR31734; PTHR31734; 1.
DR   Pfam; PF02309; AUX_IAA; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   2: Evidence at transcript level;
KW   Auxin signaling pathway; Nucleus; Reference proteome; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..195
FT                   /note="Auxin-induced protein AUX22"
FT                   /id="PRO_0000112868"
FT   DOMAIN          86..174
FT                   /note="PB1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT   REGION          37..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           13..17
FT                   /note="EAR-like (transcriptional repression)"
SQ   SEQUENCE   195 AA;  21528 MW;  ED1E50F2B3A288B3 CRC64;
     MAKEGLGLEI TELRLGLPDA EHQVSVVNKK NEKKRAFSEI DDGVGDENSS SGGGDRKMET
     NKSQVVGWPP VCSYRKKNSM NEGASKMYVK VSMDGAPFLR KIDLGLHKGY SDLALALDKL
     FGCYGMVEAL KNADNSEHVP IYEDKDGDWM LVGDVPWEMF MESCKRLRIM KKSDAKGFGL
     QPKGSLKGFI ESAAK