ID   AV2_MYMVV               Reviewed;         116 AA.
AC   Q9YPS6;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   12-AUG-2020, entry version 43.
DE   RecName: Full=Protein AV2;
GN   ORFNames=AV2;
OS   Mungbean yellow mosaic virus (strain Vigna) (MYMV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=223295;
OH   NCBI_TaxID=3847; Glycine max (Soybean) (Glycine hispida).
OH   NCBI_TaxID=3915; Vigna mungo (Black gram) (Phaseolus mungo).
OH   NCBI_TaxID=157791; Vigna radiata (Mung bean).
OH   NCBI_TaxID=3916; Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OH   NCBI_TaxID=3917; Vigna unguiculata (Cowpea).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15290387; DOI=10.1007/s00705-004-0313-z;
RA   Karthikeyan A.S., Vanitharani R., Balaji V., Anuradha S.,
RA   Thillaichidambaram P., Shivaprasad P.V., Parameswari C., Balamani V.,
RA   Saminathan M., Veluthambi K.;
RT   "Analysis of an isolate of Mungbean yellow mosaic virus (MYMV) with a
RT   highly variable DNA B component.";
RL   Arch. Virol. 149:1643-1652(2004).
CC   -!- FUNCTION: Through its interaction with host SGS3, acts as a suppressor
CC       of RNA-mediated gene silencing, also known as post-transcriptional gene
CC       silencing (PTGS), a mechanism of plant viral defense that limits the
CC       accumulation of viral RNAs. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with host SGS3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm, host perinuclear region
CC       {ECO:0000250}. Note=Accumulates in inclusion bodies in the cell
CC       periphery. May interact with the ER network from the perinuclear region
CC       out to the cell periphery (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae protein AV2/V2 family.
CC       {ECO:0000305}.
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DR   EMBL; AJ132575; CAA10703.1; -; Genomic_DNA.
DR   Proteomes; UP000007784; Genome.
DR   GO; GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019048; P:modulation by virus of host process; IEA:InterPro.
DR   GO; GO:0060967; P:negative regulation of gene silencing by RNA; IEA:InterPro.
DR   InterPro; IPR002511; Gemini_V2.
DR   Pfam; PF01524; Gemini_V2; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host-virus interaction; Reference proteome;
KW   Suppressor of RNA silencing.
FT   CHAIN           1..116
FT                   /note="Protein AV2"
FT                   /id="PRO_0000323700"
SQ   SEQUENCE   116 AA;  13594 MW;  C5FCCFF17AF4882C CRC64;
     MWDPLVNDFP KSLHGFRCML AIKYLQYIQE NYPSNSLGFV YLTELIQVLR IRKHAKAELR
     YRLLYPDVEC AEEADLRHPA FLTCHCGKCP CQREKEEVDQ PTHVEETEIL SVIPLS