ID   AVLA2_WHEAT             Reviewed;         179 AA.
AC   P0CZ07;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Avenin-like a2;
DE   Flags: Precursor;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Cadenza;
RX   DOI=10.1016/j.jcs.2006.04.004;
RA   Kan Y., Wan Y., Beaudoin F., Leader D.J., Edwards K., Poole R., Wang D.,
RA   Mitchell R.A.C., Shewry P.R.;
RT   "Transcriptome analysis reveals differentially expressed storage protein
RT   transcripts in seeds of Aegilops and wheat.";
RL   J. Cereal Sci. 44:75-85(2006).
CC   -!- FUNCTION: Seed storage protein. Not integrated in the gluten polymer
CC       through disulfide bonds, unless incorporated by reduction and
CC       reoxidation during dough making. Increases dough strength and bread
CC       volume, but decreases dough stability when added into a base wheat
CC       flour (By similarity). {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in developing grains.
CC       {ECO:0000269|Ref.1}.
CC   -!- PTM: Contains 7 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the prolamin family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CZ07; -.
DR   Proteomes; UP000019116; Unplaced.
DR   ExpressionAtlas; P0CZ07; baseline and differential.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   CDD; cd00261; AAI_SS; 1.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR044723; AAI_SS_dom.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR   InterPro; IPR001954; Glia_glutenin.
DR   PANTHER; PTHR33454; PTHR33454; 1.
DR   Pfam; PF13016; Gliadin; 1.
DR   PRINTS; PR00208; GLIADGLUTEN.
DR   SMART; SM00499; AAI; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Seed storage protein; Signal;
KW   Storage protein.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..179
FT                   /note="Avenin-like a2"
FT                   /id="PRO_0000410693"
SQ   SEQUENCE   179 AA;  19702 MW;  7635B9BDC618FE3E CRC64;
     MKTMFLLALL AFTATSAVAQ LYTTCSQGYG QCQQQPQPQP QPQPQMNTCA AFLQQCIQTP
     YVQSQMWQAS GCQLMRQQCC QPLAQISEQA RCQAVCSVSQ IIMRQQQGQR FGQPQQQQGQ
     SFGQPQQQVP VEIMRMVLQT LPSMCSVNIP QYCTTTPCST ITPAIYSIPM TATCAGGAC