ID   AVLA3_WHEAT             Reviewed;         175 AA.
AC   P0CZ08;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 28.
DE   RecName: Full=Avenin-like a3;
DE   Flags: Precursor;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Cadenza;
RX   DOI=10.1016/j.jcs.2006.04.004;
RA   Kan Y., Wan Y., Beaudoin F., Leader D.J., Edwards K., Poole R., Wang D.,
RA   Mitchell R.A.C., Shewry P.R.;
RT   "Transcriptome analysis reveals differentially expressed storage protein
RT   transcripts in seeds of Aegilops and wheat.";
RL   J. Cereal Sci. 44:75-85(2006).
CC   -!- FUNCTION: Seed storage protein. Not integrated in the gluten polymer
CC       through disulfide bonds, unless incorporated by reduction and
CC       reoxidation during dough making. Increases dough strength and bread
CC       volume, but decreases dough stability when added into a base wheat
CC       flour (By similarity). {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in developing grains.
CC       {ECO:0000269|Ref.1}.
CC   -!- PTM: Contains 7 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the prolamin family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CZ08; -.
DR   PRIDE; P0CZ08; -.
DR   Proteomes; UP000019116; Unplaced.
DR   ExpressionAtlas; P0CZ08; baseline and differential.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   CDD; cd00261; AAI_SS; 1.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR044723; AAI_SS_dom.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR   InterPro; IPR001954; Glia_glutenin.
DR   PANTHER; PTHR33454; PTHR33454; 1.
DR   Pfam; PF13016; Gliadin; 1.
DR   PRINTS; PR00208; GLIADGLUTEN.
DR   SMART; SM00499; AAI; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Seed storage protein; Signal;
KW   Storage protein.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..175
FT                   /note="Avenin-like a3"
FT                   /id="PRO_0000410694"
SQ   SEQUENCE   175 AA;  19251 MW;  70167C887918A8E2 CRC64;
     MKTMFLLALL AFTATSAVAQ LYTTCSQGYG QCQQQPQPQP QMNTCAAFLQ QCIQTPYVQS
     QMWQASGCQL MRQQCCQPLA QISEQARCQA VCSVSQIIMR QQQGQRFGQP QQQQGQSFGQ
     PQQQVPVEIM RMVLQTLPSM CSVNIPQYCT TTPCSTITPA IYSIPMTATC AGGAC