ID   AVLA4_WHEAT             Reviewed;         172 AA.
AC   D2KFH1;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   09-FEB-2010, sequence version 1.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Avenin-like a4;
DE   Flags: Precursor;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Cheyenne;
RX   AGRICOLA=IND23233454;
RA   Anderson O.D., Hsia C.C., Adalsteins A.E., Lew E.J., Kasarda D.D.;
RT   "Identification of several new classes of low-molecular-weight wheat
RT   gliadin-related proteins and genes.";
RL   Theor. Appl. Genet. 103:307-315(2001).
CC   -!- FUNCTION: Seed storage protein. Not integrated in the gluten polymer
CC       through disulfide bonds, unless incorporated by reduction and
CC       reoxidation during dough making. Increases dough strength and bread
CC       volume, but decreases dough stability when added into a base wheat
CC       flour (By similarity). {ECO:0000250}.
CC   -!- PTM: Contains 7 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the prolamin family. {ECO:0000305}.
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DR   EMBL; GU211170; ADA62374.1; -; mRNA.
DR   AlphaFoldDB; D2KFH1; -.
DR   PRIDE; D2KFH1; -.
DR   EnsemblPlants; TraesPAR_scaffold_080465_01G000100.1; TraesPAR_scaffold_080465_01G000100.1; TraesPAR_scaffold_080465_01G000100.
DR   Gramene; TraesPAR_scaffold_080465_01G000100.1; TraesPAR_scaffold_080465_01G000100.1; TraesPAR_scaffold_080465_01G000100.
DR   Proteomes; UP000019116; Unplaced.
DR   ExpressionAtlas; D2KFH1; baseline.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   CDD; cd00261; AAI_SS; 1.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR044723; AAI_SS_dom.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR   InterPro; IPR001954; Glia_glutenin.
DR   PANTHER; PTHR33454; PTHR33454; 1.
DR   Pfam; PF13016; Gliadin; 1.
DR   PRINTS; PR00208; GLIADGLUTEN.
DR   SMART; SM00499; AAI; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Seed storage protein; Signal;
KW   Storage protein.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..172
FT                   /note="Avenin-like a4"
FT                   /id="PRO_0000410695"
SQ   SEQUENCE   172 AA;  18916 MW;  1650577B94AF6351 CRC64;
     MKTMFILALI ALAATSVVAQ LDTTCSQGYG QCQQQPQQQV NTCSALLQQC SPTPYVQSQM
     WQASGCQLMR QQCCQPLAQI SEQARCQAVC SVAQVIMRQQ QGQSFGQPQQ QVQSFSQPQH
     QVPIEITRMV LQTLPSMCNV NIPQYCTTTP CRTITQTPYN IPMSATCVGG TC