ID   RRAB_AERHH              Reviewed;         115 AA.
AC   A0KNU5;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Regulator of ribonuclease activity B {ECO:0000255|HAMAP-Rule:MF_01888};
GN   Name=rraB {ECO:0000255|HAMAP-Rule:MF_01888}; OrderedLocusNames=AHA_3470;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS   13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC
RC   2358 / NCIMB 9240 / NCTC 8049;
RX   PubMed=16980456; DOI=10.1128/jb.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Globally modulates RNA abundance by binding to RNase E (Rne)
CC       and regulating its endonucleolytic activity. Can modulate Rne action in
CC       a substrate-dependent manner by altering the composition of the
CC       degradosome. {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBUNIT: Interacts with the C-terminal region of Rne.
CC       {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SIMILARITY: Belongs to the RraB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01888}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK38186.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CP000462; ABK38186.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_076360509.1; NC_008570.1.
DR   RefSeq; YP_857946.1; NC_008570.1.
DR   AlphaFoldDB; A0KNU5; -.
DR   SMR; A0KNU5; -.
DR   STRING; 380703.AHA_3470; -.
DR   EnsemblBacteria; ABK38186; ABK38186; AHA_3470.
DR   GeneID; 64360003; -.
DR   KEGG; aha:AHA_3470; -.
DR   PATRIC; fig|380703.7.peg.3460; -.
DR   eggNOG; COG3076; Bacteria.
DR   HOGENOM; CLU_1583088_0_0_6; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0060698; F:endoribonuclease inhibitor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.970; -; 1.
DR   HAMAP; MF_01888; RraB; 1.
DR   InterPro; IPR016716; RraB.
DR   InterPro; IPR036701; RraB-like_sf.
DR   InterPro; IPR009671; RraB_dom.
DR   Pfam; PF06877; RraB; 1.
DR   PIRSF; PIRSF018193; UCP018193; 1.
DR   SUPFAM; SSF89946; SSF89946; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..115
FT                   /note="Regulator of ribonuclease activity B"
FT                   /id="PRO_0000404302"
SQ   SEQUENCE   115 AA;  13103 MW;  59F962B4B531CE0D CRC64;
     MSLDMQEWRE ETTAIVNELL ADGSNPDLEY EIEHHFACQD FDLLEKAAVD LFKAGFEVTD
     AEEMELDDGA TIFCFDATTE CKLDIETIVA DIAKMLPILE KYGVDYDGWG TYFQE