ID   RRAB_AERS4              Reviewed;         115 AA.
AC   A4SJC2;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Regulator of ribonuclease activity B {ECO:0000255|HAMAP-Rule:MF_01888};
GN   Name=rraB {ECO:0000255|HAMAP-Rule:MF_01888}; OrderedLocusNames=ASA_0850;
OS   Aeromonas salmonicida (strain A449).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=382245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A449;
RX   PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA   Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA   Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA   Brown L.L.;
RT   "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT   the evolution of a fish pathogen.";
RL   BMC Genomics 9:427-427(2008).
CC   -!- FUNCTION: Globally modulates RNA abundance by binding to RNase E (Rne)
CC       and regulating its endonucleolytic activity. Can modulate Rne action in
CC       a substrate-dependent manner by altering the composition of the
CC       degradosome. {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBUNIT: Interacts with the C-terminal region of Rne.
CC       {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SIMILARITY: Belongs to the RraB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01888}.
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DR   EMBL; CP000644; ABO88994.1; -; Genomic_DNA.
DR   RefSeq; WP_011898395.1; NC_009348.1.
DR   AlphaFoldDB; A4SJC2; -.
DR   SMR; A4SJC2; -.
DR   STRING; 382245.ASA_0850; -.
DR   EnsemblBacteria; ABO88994; ABO88994; ASA_0850.
DR   KEGG; asa:ASA_0850; -.
DR   eggNOG; COG3076; Bacteria.
DR   HOGENOM; CLU_128640_0_0_6; -.
DR   OMA; FCFDAIA; -.
DR   Proteomes; UP000000225; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0060698; F:endoribonuclease inhibitor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.970; -; 1.
DR   HAMAP; MF_01888; RraB; 1.
DR   InterPro; IPR016716; RraB.
DR   InterPro; IPR036701; RraB-like_sf.
DR   InterPro; IPR009671; RraB_dom.
DR   Pfam; PF06877; RraB; 1.
DR   PIRSF; PIRSF018193; UCP018193; 1.
DR   SUPFAM; SSF89946; SSF89946; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..115
FT                   /note="Regulator of ribonuclease activity B"
FT                   /id="PRO_0000404303"
SQ   SEQUENCE   115 AA;  13164 MW;  D7AE01E566CD29F8 CRC64;
     MSLDMQEWRA ETTAIVNELL ADGSNPDLEY DIEHHFACQD FDQLEKAAVD LFKAGFEVTD
     AEEMELDDGA PIFCFDATIE RKLDIETIVA DIEKMLPILK KYGVDYDGWG TYFQE