ID   RRAB_ALTMD              Reviewed;         132 AA.
AC   B4RWP8; F2G2N2;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Regulator of ribonuclease activity B {ECO:0000255|HAMAP-Rule:MF_01888};
GN   Name=rraB {ECO:0000255|HAMAP-Rule:MF_01888};
GN   OrderedLocusNames=MADE_1016015;
OS   Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep
OS   ecotype).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX   NCBI_TaxID=1774373;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype;
RX   PubMed=18670397; DOI=10.1038/ismej.2008.74;
RA   Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A., Ferriera S.,
RA   Johnson J., Friedman R., Rodriguez-Valera F.;
RT   "Comparative genomics of two ecotypes of the marine planktonic copiotroph
RT   Alteromonas macleodii suggests alternative lifestyles associated with
RT   different kinds of particulate organic matter.";
RL   ISME J. 2:1194-1212(2008).
CC   -!- FUNCTION: Globally modulates RNA abundance by binding to RNase E (Rne)
CC       and regulating its endonucleolytic activity. Can modulate Rne action in
CC       a substrate-dependent manner by altering the composition of the
CC       degradosome. {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBUNIT: Interacts with the C-terminal region of Rne.
CC       {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SIMILARITY: Belongs to the RraB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01888}.
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DR   EMBL; CP001103; AEA99333.1; -; Genomic_DNA.
DR   RefSeq; WP_012519625.1; NC_011138.3.
DR   AlphaFoldDB; B4RWP8; -.
DR   SMR; B4RWP8; -.
DR   EnsemblBacteria; AEA99333; AEA99333; MADE_1016015.
DR   GeneID; 56343476; -.
DR   KEGG; amc:MADE_1016015; -.
DR   HOGENOM; CLU_128640_0_0_6; -.
DR   OMA; FCFDAIA; -.
DR   Proteomes; UP000001870; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0060698; F:endoribonuclease inhibitor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.970; -; 1.
DR   HAMAP; MF_01888; RraB; 1.
DR   InterPro; IPR016716; RraB.
DR   InterPro; IPR036701; RraB-like_sf.
DR   InterPro; IPR009671; RraB_dom.
DR   Pfam; PF06877; RraB; 1.
DR   PIRSF; PIRSF018193; UCP018193; 1.
DR   SUPFAM; SSF89946; SSF89946; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..132
FT                   /note="Regulator of ribonuclease activity B"
FT                   /id="PRO_0000404304"
SQ   SEQUENCE   132 AA;  15238 MW;  EF4D8EDF1E68388D CRC64;
     MNQFDEREEW YAFNQETIDA LLEDGSQADA DYTIEHHFAS TDFDVLEKAA VDAFKAGFEV
     TDAEELMLDD GETIFCFDAV VERKLDIEKL NADADALLKI ADKHDVTYDG WGTYFEPREE
     GEYEEEEHHL ND