ID   RRAB_CROTZ              Reviewed;         140 AA.
AC   C9XUB3;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 2.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Regulator of ribonuclease activity B {ECO:0000255|HAMAP-Rule:MF_01888};
GN   Name=rraB {ECO:0000255|HAMAP-Rule:MF_01888}; OrderedLocusNames=Ctu_04960;
OS   Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=693216;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18703 / CCUG 55852 / LMG 23827 / z3032;
RX   PubMed=21037008; DOI=10.1128/jb.01162-10;
RA   Stephan R., Lehner A., Tischler P., Rattei T.;
RT   "Complete genome sequence of Cronobacter turicensis LMG 23827, a food-borne
RT   pathogen causing deaths in neonates.";
RL   J. Bacteriol. 193:309-310(2011).
CC   -!- FUNCTION: Globally modulates RNA abundance by binding to RNase E (Rne)
CC       and regulating its endonucleolytic activity. Can modulate Rne action in
CC       a substrate-dependent manner by altering the composition of the
CC       degradosome. {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBUNIT: Interacts with the C-terminal region of Rne.
CC       {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SIMILARITY: Belongs to the RraB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01888}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CBA27575.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN543093; CBA27575.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041923131.1; NC_013282.2.
DR   AlphaFoldDB; C9XUB3; -.
DR   SMR; C9XUB3; -.
DR   EnsemblBacteria; CBA27575; CBA27575; CTU_04960.
DR   GeneID; 60372182; -.
DR   KEGG; ctu:CTU_04960; -.
DR   PATRIC; fig|693216.3.peg.475; -.
DR   HOGENOM; CLU_128640_0_0_6; -.
DR   Proteomes; UP000002069; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0060698; F:endoribonuclease inhibitor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.970; -; 1.
DR   HAMAP; MF_01888; RraB; 1.
DR   InterPro; IPR016716; RraB.
DR   InterPro; IPR036701; RraB-like_sf.
DR   InterPro; IPR009671; RraB_dom.
DR   Pfam; PF06877; RraB; 1.
DR   PIRSF; PIRSF018193; UCP018193; 1.
DR   SUPFAM; SSF89946; SSF89946; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..140
FT                   /note="Regulator of ribonuclease activity B"
FT                   /id="PRO_0000404306"
FT   REGION          113..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        115..133
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   140 AA;  15901 MW;  ED6257FB8A6A2DC6 CRC64;
     MANPELLEEQ REETRLIIEE LLEDGSDPEA LYTIEHHFSA DDFDTLEKLA VEVFKLGYEV
     TDPEELELEE GGETVICCDA LSECALNAEL IDAQVEQLMN MAEKFNVEYD GWGTYFEDPD
     GEGEDEDDEG MDEDDDGVRH