ID   RRAB_IDILO              Reviewed;         128 AA.
AC   Q5QY14;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Regulator of ribonuclease activity B {ECO:0000255|HAMAP-Rule:MF_01888};
GN   Name=rraB {ECO:0000255|HAMAP-Rule:MF_01888}; OrderedLocusNames=IL1951;
OS   Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Idiomarinaceae; Idiomarina.
OX   NCBI_TaxID=283942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-735 / DSM 15497 / L2-TR;
RX   PubMed=15596722; DOI=10.1073/pnas.0407638102;
RA   Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y.,
RA   Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S.,
RA   Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S., Campbell S.,
RA   Denery J., Aizawa S., Shibata S., Malahoff A., Alam M.;
RT   "Genome sequence of the deep-sea gamma-proteobacterium Idiomarina
RT   loihiensis reveals amino acid fermentation as a source of carbon and
RT   energy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004).
CC   -!- FUNCTION: Globally modulates RNA abundance by binding to RNase E (Rne)
CC       and regulating its endonucleolytic activity. Can modulate Rne action in
CC       a substrate-dependent manner by altering the composition of the
CC       degradosome. {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBUNIT: Interacts with the C-terminal region of Rne.
CC       {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SIMILARITY: Belongs to the RraB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01888}.
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DR   EMBL; AE017340; AAV82783.1; -; Genomic_DNA.
DR   RefSeq; WP_011235179.1; NC_006512.1.
DR   AlphaFoldDB; Q5QY14; -.
DR   SMR; Q5QY14; -.
DR   STRING; 283942.IL1951; -.
DR   EnsemblBacteria; AAV82783; AAV82783; IL1951.
DR   KEGG; ilo:IL1951; -.
DR   eggNOG; COG3076; Bacteria.
DR   HOGENOM; CLU_128640_0_0_6; -.
DR   OMA; FCFDAIA; -.
DR   OrthoDB; 1479816at2; -.
DR   Proteomes; UP000001171; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0060698; F:endoribonuclease inhibitor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.970; -; 1.
DR   HAMAP; MF_01888; RraB; 1.
DR   InterPro; IPR016716; RraB.
DR   InterPro; IPR036701; RraB-like_sf.
DR   InterPro; IPR009671; RraB_dom.
DR   Pfam; PF06877; RraB; 1.
DR   PIRSF; PIRSF018193; UCP018193; 1.
DR   SUPFAM; SSF89946; SSF89946; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..128
FT                   /note="Regulator of ribonuclease activity B"
FT                   /id="PRO_0000404308"
SQ   SEQUENCE   128 AA;  14641 MW;  646315879CFA2D1D CRC64;
     MSRDLNDLLT QSEETVQALI ADGAETELLY EIEHHLASQD FTKLEKAAVE LVKQGYHVDD
     ADEFEDERGK RWFAFMAVTD AELDNDILNR QVREIAAIAD ECEVEYDGWG TLIEDEELDD
     EDLDDGEE