ID   RRAB_PHOPR              Reviewed;         135 AA.
AC   Q6LUW5;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Regulator of ribonuclease activity B {ECO:0000255|HAMAP-Rule:MF_01888};
GN   Name=rraB {ECO:0000255|HAMAP-Rule:MF_01888}; OrderedLocusNames=PBPRA0479;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Globally modulates RNA abundance by binding to RNase E (Rne)
CC       and regulating its endonucleolytic activity. Can modulate Rne action in
CC       a substrate-dependent manner by altering the composition of the
CC       degradosome. {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBUNIT: Interacts with the C-terminal region of Rne.
CC       {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01888}.
CC   -!- SIMILARITY: Belongs to the RraB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01888}.
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DR   EMBL; CR378664; CAG18910.1; -; Genomic_DNA.
DR   RefSeq; WP_011217266.1; NC_006370.1.
DR   AlphaFoldDB; Q6LUW5; -.
DR   SMR; Q6LUW5; -.
DR   STRING; 298386.PBPRA0479; -.
DR   EnsemblBacteria; CAG18910; CAG18910; PBPRA0479.
DR   KEGG; ppr:PBPRA0479; -.
DR   eggNOG; COG3076; Bacteria.
DR   HOGENOM; CLU_128640_0_0_6; -.
DR   OMA; FCFDAIA; -.
DR   OrthoDB; 1479816at2; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0060698; F:endoribonuclease inhibitor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019899; F:enzyme binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.970; -; 1.
DR   HAMAP; MF_01888; RraB; 1.
DR   InterPro; IPR016716; RraB.
DR   InterPro; IPR036701; RraB-like_sf.
DR   InterPro; IPR009671; RraB_dom.
DR   Pfam; PF06877; RraB; 1.
DR   PIRSF; PIRSF018193; UCP018193; 1.
DR   SUPFAM; SSF89946; SSF89946; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..135
FT                   /note="Regulator of ribonuclease activity B"
FT                   /id="PRO_0000404310"
FT   REGION          114..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        115..135
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   135 AA;  15058 MW;  212FDB343EB371CD CRC64;
     MSYAELIEEQ KEETRDIIAA LLEDGSEPEA LYTIEHHFSA DTFAELEAAA VEAFKMGFEV
     LEAEELELAP EDGGGKVVCF DAVMESALNA ELIDEQTEKL IALADKHDID YDGWGTYFES
     DEDDEEDESE DKPEA