ID   RRFM_RAT                Reviewed;         262 AA.
AC   Q5RKI9;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Ribosome-recycling factor, mitochondrial;
DE            Short=RRF;
DE   AltName: Full=Ribosome-releasing factor, mitochondrial;
DE   Flags: Precursor;
GN   Name=Mrrf;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC       at the termination of protein biosynthesis. May increase the efficiency
CC       of translation by recycling ribosomes from one round of translation to
CC       another (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRF family. {ECO:0000305}.
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DR   EMBL; BC085779; AAH85779.1; -; mRNA.
DR   RefSeq; NP_001008355.1; NM_001008354.1.
DR   AlphaFoldDB; Q5RKI9; -.
DR   SMR; Q5RKI9; -.
DR   STRING; 10116.ENSRNOP00000038041; -.
DR   iPTMnet; Q5RKI9; -.
DR   PhosphoSitePlus; Q5RKI9; -.
DR   jPOST; Q5RKI9; -.
DR   PaxDb; Q5RKI9; -.
DR   PRIDE; Q5RKI9; -.
DR   Ensembl; ENSRNOT00000033047; ENSRNOP00000038041; ENSRNOG00000025997.
DR   GeneID; 311903; -.
DR   KEGG; rno:311903; -.
DR   UCSC; RGD:1305897; rat.
DR   CTD; 92399; -.
DR   RGD; 1305897; Mrrf.
DR   eggNOG; KOG4759; Eukaryota.
DR   GeneTree; ENSGT00390000005084; -.
DR   HOGENOM; CLU_073981_4_1_1; -.
DR   InParanoid; Q5RKI9; -.
DR   OMA; FNPMNNG; -.
DR   OrthoDB; 1472838at2759; -.
DR   PhylomeDB; Q5RKI9; -.
DR   TreeFam; TF323691; -.
DR   Reactome; R-RNO-5419276; Mitochondrial translation termination.
DR   PRO; PR:Q5RKI9; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000025997; Expressed in heart and 19 other tissues.
DR   Genevisible; Q5RKI9; RN.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IBA:GO_Central.
DR   GO; GO:0032790; P:ribosome disassembly; ISO:RGD.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   Gene3D; 1.10.132.20; -; 1.
DR   InterPro; IPR002661; Ribosome_recyc_fac.
DR   InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR   InterPro; IPR036191; RRF_sf.
DR   PANTHER; PTHR20982; PTHR20982; 1.
DR   Pfam; PF01765; RRF; 1.
DR   SUPFAM; SSF55194; SSF55194; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Protein biosynthesis; Reference proteome; Transit peptide.
FT   TRANSIT         1..55
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           56..262
FT                   /note="Ribosome-recycling factor, mitochondrial"
FT                   /id="PRO_0000031082"
SQ   SEQUENCE   262 AA;  29152 MW;  45A480E3E4565008 CRC64;
     MALGIRCFRL LHPAFSSYLA DLSRPVSEVP MKTVRGRQRD HIQYSAHPAV PVRQFATKKA
     KAKGKGQPQA RVNINTALVE DIISLEEVDE DMKSVMEALK DNFNKTLNIR TAPGSLDHIT
     VVTADGKLAL NQIGQISMKS PQLILVNMAS FPECTAAAIK AIRESGMNLN PEVEGTLIRV
     PIPKVTREHR EMLVKLAKQN TNKAKENLRK VRTNAMNKLK KSKDKTSEDT IRLIEKQISQ
     MADDTVAELD RHLAAKTKEL LG