RRF_AKKM8
ID RRF_AKKM8 Reviewed; 188 AA.
AC B2UKL9;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040};
DE Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040};
DE AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040};
GN Name=frr {ECO:0000255|HAMAP-Rule:MF_00040}; OrderedLocusNames=Amuc_1318;
OS Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS 81048 / CCUG 64013 / CIP 107961 / Muc).
OC Bacteria; Verrucomicrobia; Verrucomicrobiae; Verrucomicrobiales;
OC Akkermansiaceae; Akkermansia.
OX NCBI_TaxID=349741;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP
RC 107961 / Muc;
RX PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT degrader, and its use in exploring intestinal metagenomes.";
RL PLoS ONE 6:E16876-E16876(2011).
CC -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC at the termination of protein biosynthesis. May increase the efficiency
CC of translation by recycling ribosomes from one round of translation to
CC another. {ECO:0000255|HAMAP-Rule:MF_00040}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}.
CC -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP-
CC Rule:MF_00040}.
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DR EMBL; CP001071; ACD05142.1; -; Genomic_DNA.
DR RefSeq; WP_012420357.1; NC_010655.1.
DR AlphaFoldDB; B2UKL9; -.
DR SMR; B2UKL9; -.
DR STRING; 349741.Amuc_1318; -.
DR EnsemblBacteria; ACD05142; ACD05142; Amuc_1318.
DR GeneID; 60880842; -.
DR KEGG; amu:Amuc_1318; -.
DR eggNOG; COG0233; Bacteria.
DR HOGENOM; CLU_073981_2_0_0; -.
DR OMA; FNPMNNG; -.
DR OrthoDB; 1674344at2; -.
DR BioCyc; AMUC349741:G1GBX-1407-MON; -.
DR Proteomes; UP000001031; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule.
DR CDD; cd00520; RRF; 1.
DR Gene3D; 1.10.132.20; -; 1.
DR HAMAP; MF_00040; RRF; 1.
DR InterPro; IPR002661; Ribosome_recyc_fac.
DR InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR InterPro; IPR036191; RRF_sf.
DR PANTHER; PTHR20982; PTHR20982; 1.
DR Pfam; PF01765; RRF; 1.
DR SUPFAM; SSF55194; SSF55194; 1.
DR TIGRFAMs; TIGR00496; frr; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Protein biosynthesis; Reference proteome.
FT CHAIN 1..188
FT /note="Ribosome-recycling factor"
FT /id="PRO_1000090702"
SQ SEQUENCE 188 AA; 20903 MW; 400B720F1D152D39 CRC64;
MDAETLLLET EESMLKAVDF AKQEFSGVRT GKASPGLVEN LDVHVSSYGS VMKLKGLAVI
STPEPRLILI QPFDPSTVHD IGRAINESKL NLNPLVEGRS IRLPIPALTE ERRKDLVKLV
KSQAEEARVR VRGARKAAMD SAKKLKAENI VTEDGQRDLE TQIQKLTDKY VKEIDELVAV
KEKDIMTI