RRF_BRUME
ID RRF_BRUME Reviewed; 186 AA.
AC P94340;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040};
DE Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040};
DE AltName: Full=CP24;
DE AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040};
GN Name=frr {ECO:0000255|HAMAP-Rule:MF_00040}; Synonyms=cp24;
GN OrderedLocusNames=BMEI0826;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=8890247; DOI=10.1128/iai.64.11.4834-4837.1996;
RA Vizcaino N., Cloeckaert A., Dubray G., Zygmunt M.S.;
RT "Cloning, nucleotide sequence, and expression of the gene coding for a
RT ribosome releasing factor-homologous protein of Brucella melitensis.";
RL Infect. Immun. 64:4834-4837(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC at the termination of protein biosynthesis. May increase the efficiency
CC of translation by recycling ribosomes from one round of translation to
CC another. {ECO:0000255|HAMAP-Rule:MF_00040}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}.
CC -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP-
CC Rule:MF_00040}.
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DR EMBL; U53133; AAB19043.1; -; Genomic_DNA.
DR EMBL; AE008917; AAL52007.1; -; Genomic_DNA.
DR PIR; AD3355; AD3355.
DR RefSeq; WP_004683873.1; NZ_GG703780.1.
DR AlphaFoldDB; P94340; -.
DR SMR; P94340; -.
DR STRING; 224914.BMEI0826; -.
DR EnsemblBacteria; AAL52007; AAL52007; BMEI0826.
DR GeneID; 29593640; -.
DR KEGG; bme:BMEI0826; -.
DR PATRIC; fig|224914.52.peg.619; -.
DR eggNOG; COG0233; Bacteria.
DR OMA; FNPMNNG; -.
DR PhylomeDB; P94340; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule.
DR CDD; cd00520; RRF; 1.
DR Gene3D; 1.10.132.20; -; 1.
DR HAMAP; MF_00040; RRF; 1.
DR InterPro; IPR002661; Ribosome_recyc_fac.
DR InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR InterPro; IPR036191; RRF_sf.
DR PANTHER; PTHR20982; PTHR20982; 1.
DR Pfam; PF01765; RRF; 1.
DR SUPFAM; SSF55194; SSF55194; 1.
DR TIGRFAMs; TIGR00496; frr; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Protein biosynthesis.
FT CHAIN 1..186
FT /note="Ribosome-recycling factor"
FT /id="PRO_0000167426"
SQ SEQUENCE 186 AA; 20723 MW; 5CF102288A21B3A1 CRC64;
MSDAFDINDL KRRMEGAVNA LKHDLGGLRT GRASASLLEP ITIEAYGSTM PINQVANISV
PESRMLSVSV WDKSMVGAVE RAIRDSGLGL NPITDGMTLR IRLPELNEQR RKELVKIAHQ
YAEQGRIAAR HVRRDGMDQL KKLEKDSVIS QDESRVLSEK VQKLTDDTIA EMDKIVAVKE
GEIMQV
