ID   AVPL_EISFE              Reviewed;          11 AA.
AC   P86931;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   03-AUG-2022, entry version 13.
DE   RecName: Full=Antiviral serine protease {ECO:0000303|PubMed:18775500};
DE            EC=3.4.21.- {ECO:0000269|PubMed:18775500};
DE   Flags: Fragment;
OS   Eisenia fetida (Red wiggler worm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC   Oligochaeta; Crassiclitellata; Lumbricina; Lumbricidae; Lumbricinae;
OC   Eisenia.
OX   NCBI_TaxID=6396;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AND BIOPHYSICOCHEMICAL PROPERTIES.
RC   TISSUE=Coelomic fluid {ECO:0000269|PubMed:18775500};
RX   PubMed=18775500; DOI=10.1016/j.cbpb.2008.08.005;
RA   Ueda M., Noda K., Nakazawa M., Miyatake K., Ohki S., Sakaguchi M.,
RA   Inouye K.;
RT   "A novel anti-plant viral protein from coelomic fluid of the earthworm
RT   Eisenia foetida: purification, characterization and its identification as a
RT   serine protease.";
RL   Comp. Biochem. Physiol. 151:381-385(2008).
CC   -!- FUNCTION: Serine protease which has antiviral activity against cucumber
CC       mosaic virus and tobacco mosaic virus. {ECO:0000269|PubMed:18775500}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Optimum pH is 9.5. Active from pH 7.0 to 10.0.
CC         {ECO:0000269|PubMed:18775500};
CC       Temperature dependence:
CC         Thermostable. Optimum temperature is 40-50 degrees Celsius. Stable up
CC         to 60 degrees Celsius and retains 60% of activity at 4 degrees
CC         Celsius. {ECO:0000269|PubMed:18775500};
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DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antiviral protein; Direct protein sequencing; Hydrolase; Protease;
KW   Serine protease.
FT   CHAIN           1..>11
FT                   /note="Antiviral serine protease"
FT                   /id="PRO_0000411992"
FT   NON_TER         11
FT                   /evidence="ECO:0000303|PubMed:18775500"
SQ   SEQUENCE   11 AA;  952 MW;  232F3FD3DDCAE878 CRC64;
     VIAGGXAAII G