ID   RRF_ECO24               Reviewed;         185 AA.
AC   A7ZHR2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040};
DE            Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040};
DE   AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040};
GN   Name=frr {ECO:0000255|HAMAP-Rule:MF_00040};
GN   OrderedLocusNames=EcE24377A_0176;
OS   Escherichia coli O139:H28 (strain E24377A / ETEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=331111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E24377A / ETEC;
RX   PubMed=18676672; DOI=10.1128/jb.00619-08;
RA   Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA   Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA   Henderson I.R., Sperandio V., Ravel J.;
RT   "The pangenome structure of Escherichia coli: comparative genomic analysis
RT   of E. coli commensal and pathogenic isolates.";
RL   J. Bacteriol. 190:6881-6893(2008).
CC   -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC       at the termination of protein biosynthesis. May increase the efficiency
CC       of translation by recycling ribosomes from one round of translation to
CC       another. {ECO:0000255|HAMAP-Rule:MF_00040}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}.
CC   -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP-
CC       Rule:MF_00040}.
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DR   EMBL; CP000800; ABV16949.1; -; Genomic_DNA.
DR   RefSeq; WP_000622418.1; NC_009801.1.
DR   AlphaFoldDB; A7ZHR2; -.
DR   BMRB; A7ZHR2; -.
DR   SMR; A7ZHR2; -.
DR   EnsemblBacteria; ABV16949; ABV16949; EcE24377A_0176.
DR   GeneID; 67416248; -.
DR   KEGG; ecw:EcE24377A_0176; -.
DR   HOGENOM; CLU_073981_2_1_6; -.
DR   OMA; FNPMNNG; -.
DR   Proteomes; UP000001122; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule.
DR   CDD; cd00520; RRF; 1.
DR   Gene3D; 1.10.132.20; -; 1.
DR   HAMAP; MF_00040; RRF; 1.
DR   InterPro; IPR002661; Ribosome_recyc_fac.
DR   InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR   InterPro; IPR036191; RRF_sf.
DR   PANTHER; PTHR20982; PTHR20982; 1.
DR   Pfam; PF01765; RRF; 1.
DR   SUPFAM; SSF55194; SSF55194; 1.
DR   TIGRFAMs; TIGR00496; frr; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cytoplasm; Protein biosynthesis.
FT   CHAIN           1..185
FT                   /note="Ribosome-recycling factor"
FT                   /id="PRO_1000057290"
FT   MOD_RES         162
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00040"
SQ   SEQUENCE   185 AA;  20639 MW;  CBFB9675AAD0CFD8 CRC64;
     MISDIRKDAE VRMDKCVEAF KTQISKIRTG RASPSLLDGI VVEYYGTPTP LRQLASVTVE
     DSRTLKINVF DRSMSPAVEK AIMASDLGLN PNSAGSDIRV PLPPLTEERR KDLTKIVRGE
     AEQARVAVRN VRRDANDKVK ALLKDKEISE DDDRRSQDDV QKLTDAAIKK IEAALADKEA
     ELMQF