ID   RRF_EHRCR               Reviewed;         185 AA.
AC   Q2GHJ5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040};
DE            Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040};
DE   AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040};
GN   Name=frr {ECO:0000255|HAMAP-Rule:MF_00040}; OrderedLocusNames=ECH_0267;
OS   Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Ehrlichia.
OX   NCBI_TaxID=205920;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC CRL-10679 / Arkansas;
RX   PubMed=16482227; DOI=10.1371/journal.pgen.0020021;
RA   Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V.,
RA   Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M.,
RA   Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N., Nelson W.C.,
RA   Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P., Daugherty S.C.,
RA   Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H., Selengut J.D.,
RA   Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R.,
RA   Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H.;
RT   "Comparative genomics of emerging human ehrlichiosis agents.";
RL   PLoS Genet. 2:208-222(2006).
CC   -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC       at the termination of protein biosynthesis. May increase the efficiency
CC       of translation by recycling ribosomes from one round of translation to
CC       another. {ECO:0000255|HAMAP-Rule:MF_00040}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}.
CC   -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP-
CC       Rule:MF_00040}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000236; ABD45378.1; -; Genomic_DNA.
DR   RefSeq; WP_011452494.1; NC_007799.1.
DR   PDB; 6VUD; X-ray; 2.35 A; A/B=1-185.
DR   PDBsum; 6VUD; -.
DR   AlphaFoldDB; Q2GHJ5; -.
DR   SMR; Q2GHJ5; -.
DR   STRING; 205920.ECH_0267; -.
DR   EnsemblBacteria; ABD45378; ABD45378; ECH_0267.
DR   KEGG; ech:ECH_0267; -.
DR   eggNOG; COG0233; Bacteria.
DR   HOGENOM; CLU_073981_2_1_5; -.
DR   OMA; FNPMNNG; -.
DR   OrthoDB; 1674344at2; -.
DR   Proteomes; UP000008320; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule.
DR   CDD; cd00520; RRF; 1.
DR   Gene3D; 1.10.132.20; -; 1.
DR   HAMAP; MF_00040; RRF; 1.
DR   InterPro; IPR002661; Ribosome_recyc_fac.
DR   InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR   InterPro; IPR036191; RRF_sf.
DR   PANTHER; PTHR20982; PTHR20982; 1.
DR   Pfam; PF01765; RRF; 1.
DR   SUPFAM; SSF55194; SSF55194; 1.
DR   TIGRFAMs; TIGR00496; frr; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..185
FT                   /note="Ribosome-recycling factor"
FT                   /id="PRO_1000003160"
FT   HELIX           2..25
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   HELIX           34..37
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   STRAND          41..44
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   STRAND          47..50
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   HELIX           51..53
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   STRAND          54..61
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   STRAND          64..71
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   HELIX           72..74
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   HELIX           75..84
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   STRAND          90..94
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   STRAND          97..101
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   HELIX           107..144
FT                   /evidence="ECO:0007829|PDB:6VUD"
FT   HELIX           150..183
FT                   /evidence="ECO:0007829|PDB:6VUD"
SQ   SEQUENCE   185 AA;  20710 MW;  3460607890F71097 CRC64;
     MISEVKQDAK SRMEKSLSVY LSDIDGIRTG RARTSVLNGI VVETYGGRVK LNTISSVSVS
     DNKTLMIKVW DSNNIGAIKT AIMNSNLGFG ISCEATTIRL TVPDMTQDMR KNLVKLLGKI
     SEDCRVSIRN IRRDIMDRLK VMQDSKEISE DDLRVAGVEI QKITDDIMKK VNDAFTSKEK
     ELLHV