AB8I_ARATH
ID AB8I_ARATH Reviewed; 557 AA.
AC Q9ZS97;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=UPF0051 protein ABCI8, chloroplastic;
DE AltName: Full=ABC transporter I family member 8;
DE Short=ABC transporter ABCI.8;
DE Short=AtABCI8;
DE AltName: Full=Non-intrinsic ABC protein 1;
DE Short=Protein ABC1;
DE AltName: Full=Plastid sufB-like protein;
DE AltName: Full=Protein LONG AFTER FAR-RED 6;
DE Flags: Precursor;
GN Name=ABCI8; Synonyms=LAF6, NAP1; OrderedLocusNames=At4g04770;
GN ORFNames=T4B21.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION, FUNCTION, SUBCELLULAR LOCATION, INDUCTION, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=11156608; DOI=10.1101/gad.850101;
RA Moeller S.G., Kunkel T., Chua N.-H.;
RT "A plastidic ABC protein involved in intercompartmental communication of
RT light signaling.";
RL Genes Dev. 15:90-103(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- FUNCTION: Involved in light signaling, probably by mediating the
CC transport and correct distribution of protoporphyrin IX, a chlorophyll
CC precursor, in response to far-red light. {ECO:0000269|PubMed:11156608}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:11156608}.
CC -!- INDUCTION: By PHYA. {ECO:0000269|PubMed:11156608}.
CC -!- DISRUPTION PHENOTYPE: Plant have an enhanced hypocotyl elongation in
CC far-red light, and accumulates protoporphyrin IX.
CC {ECO:0000269|PubMed:11156608}.
CC -!- SIMILARITY: Belongs to the UPF0051 (ycf24) family. {ECO:0000305}.
CC -!- CAUTION: Was originally (PubMed:11346655) thought to belong to the ABC
CC transporter family. Lacks the conserved ABC domain, which is one of the
CC features of the ABC transporter family. {ECO:0000305|PubMed:11346655}.
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DR EMBL; AF118223; AAD03441.1; -; Genomic_DNA.
DR EMBL; AL161501; CAB80842.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82423.1; -; Genomic_DNA.
DR EMBL; AY052195; AAK97666.1; -; mRNA.
DR EMBL; AY056410; AAL08266.1; -; mRNA.
DR EMBL; AY142069; AAM98333.1; -; mRNA.
DR EMBL; BK001497; DAA01952.1; -; mRNA.
DR PIR; A85060; A85060.
DR RefSeq; NP_192386.1; NM_116715.5.
DR AlphaFoldDB; Q9ZS97; -.
DR SMR; Q9ZS97; -.
DR BioGRID; 11125; 2.
DR IntAct; Q9ZS97; 2.
DR STRING; 3702.AT4G04770.1; -.
DR PaxDb; Q9ZS97; -.
DR PRIDE; Q9ZS97; -.
DR ProteomicsDB; 244495; -.
DR EnsemblPlants; AT4G04770.1; AT4G04770.1; AT4G04770.
DR GeneID; 825814; -.
DR Gramene; AT4G04770.1; AT4G04770.1; AT4G04770.
DR KEGG; ath:AT4G04770; -.
DR Araport; AT4G04770; -.
DR TAIR; locus:2138947; AT4G04770.
DR eggNOG; ENOG502QRGW; Eukaryota.
DR HOGENOM; CLU_026231_0_0_1; -.
DR InParanoid; Q9ZS97; -.
DR OMA; YYSAPKQ; -.
DR OrthoDB; 484141at2759; -.
DR PhylomeDB; Q9ZS97; -.
DR PRO; PR:Q9ZS97; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9ZS97; baseline and differential.
DR Genevisible; Q9ZS97; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0009570; C:chloroplast stroma; HDA:TAIR.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IDA:TAIR.
DR GO; GO:0006879; P:cellular iron ion homeostasis; IDA:TAIR.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR GO; GO:2000030; P:regulation of response to red or far red light; IMP:TAIR.
DR InterPro; IPR010231; SUF_FeS_clus_asmbl_SufB.
DR InterPro; IPR000825; SUF_FeS_clus_asmbl_SufBD.
DR InterPro; IPR037284; SUF_FeS_clus_asmbl_SufBD_sf.
DR InterPro; IPR045595; SufBD_N.
DR Pfam; PF01458; SUFBD; 1.
DR Pfam; PF19295; SufBD_N; 1.
DR SUPFAM; SSF101960; SSF101960; 1.
DR TIGRFAMs; TIGR01980; sufB; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..52
FT /note="Chloroplast"
FT /evidence="ECO:0000305"
FT CHAIN 53..557
FT /note="UPF0051 protein ABCI8, chloroplastic"
FT /id="PRO_0000250667"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 61868 MW; D68A088309CCCACE CRC64;
MASLLANGIS SFSPQPTSDS SKSPKGFHPK PESLKFPSPK SLNPTRPIFK LRADVGIDSR
PIGASESSSS GTSTVSSTDK LQQYFQNLDY DKKYGFVEDI DSFTIPKGLS EETIRLISKL
KEEPDWMLEF RFKAYAKFLK LEEPKWSDNR YPSINFQDMC YYSAPKKKPT LNSLDEVDPQ
LLEYFDKLGV PLTEQKRLAN VAVDAVIDSV SIATTHRKTL EKSGVIFCSI SEAIREYPDL
IKKYLGRVVP SDDNYYAALN SAVFSDGSFC YIPKNTRCPM PISTYFRINA METGQFERTL
IVAEEGSFVE YLEGCTAPSY DTNQLHAAVV ELYCGKGAEI KYSTVQNWYA GDEQGKGGIY
NFVTKRGLCA GDRSKISWTQ VETGSAITWK YPSVVLEGDD SVGEFYSVAL TNNYQQADTG
TKMIHKGKNT KSRIISKGIS AGHSRNCYRG LVQVQSKAEG AKNTSTCDSM LIGDKAAANT
YPYIQVKNPS AKVEHEASTS KIGEDQLFYF QQRGIDHERA LAAMISGFCR DVFNKLPDEF
GAEVNQLMSI KLEGSVG
