ID   AVRP2_PSESJ             Reviewed;         269 AA.
AC   Q9F3T4;
DT   29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Probable cysteine protease avirulence protein AvrPpiC2;
DE            EC=3.4.22.-;
GN   Name=avrPpiC2;
OS   Pseudomonas syringae pv. pisi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=59510;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=299A / Race 1;
RX   PubMed=11320120; DOI=10.1099/00221287-147-5-1171;
RA   Arnold D.L., Jackson R.W., Fillingham A.J., Goss S.C., Taylor J.D.,
RA   Mansfield J.W., Vivian A.;
RT   "Highly conserved (DNA) sequences flank avirulence genes: isolation of
RT   novel avirulence genes from Pseudomonas syringae pv pisi.";
RL   Microbiology 147:1171-1182(2001).
CC   -!- FUNCTION: Potential cysteine protease. Avirulence protein, which may be
CC       essential during infection of plant cells from Pea and some Arabidopsis
CC       thaliana cultivars. May act by affecting the plant defense system. In
CC       plants lacking appropriate resistance (R) gene, it probably impairs the
CC       plant defense system and leads to the bacteria multiplication. In
CC       contrast, in plants containing the appropriate R protein, it is unable
CC       to induce disease symptoms, explaining its avirulence name.
CC   -!- SIMILARITY: Belongs to the peptidase C58 family. {ECO:0000305}.
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DR   EMBL; AJ277496; CAC16701.1; -; Genomic_DNA.
DR   RefSeq; WP_024650469.1; NZ_RBOF01000100.1.
DR   AlphaFoldDB; Q9F3T4; -.
DR   SMR; Q9F3T4; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR006473; Peptidase_C58_Yopt.
DR   Pfam; PF03543; Peptidase_C58; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   TIGRFAMs; TIGR01586; yopT_cys_prot; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Protease; Thiol protease; Virulence.
FT   CHAIN           1..269
FT                   /note="Probable cysteine protease avirulence protein
FT                   AvrPpiC2"
FT                   /id="PRO_0000192509"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        72
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        213
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        230
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   269 AA;  28979 MW;  A255F5AC846D38B3 CRC64;
     MTIVSGHIGK HPSLTTVQAG SSASVENQMP DPAQFSDGRW KKLPTQLSSI TLARFDQNIC
     TNNHGISQRA MCFGLSLSWI NMIHAGKDHV TPYASAERMR FLGSFEGVVH ARTVHNFYRT
     EHKFLMEQAS ANPGVSSGAM AGTESLLQAA ELKGLKLQPV LEDKSNSGLP FLIACKQSGR
     QVSTDEAALS SLCDAIVENK RGVMVIYSQE IAHALGFSVS SDGKRATLFD PNLGEFHTHS
     KALADTIENI SSADGLPLIG VQVFASKIH