RRF_RICPR
ID RRF_RICPR Reviewed; 186 AA.
AC Q9ZE08;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Ribosome-recycling factor {ECO:0000255|HAMAP-Rule:MF_00040};
DE Short=RRF {ECO:0000255|HAMAP-Rule:MF_00040};
DE AltName: Full=Ribosome-releasing factor {ECO:0000255|HAMAP-Rule:MF_00040};
GN Name=frr {ECO:0000255|HAMAP-Rule:MF_00040}; OrderedLocusNames=RP154;
OS Rickettsia prowazekii (strain Madrid E).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX NCBI_TaxID=272947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Madrid E;
RX PubMed=9823893; DOI=10.1038/24094;
RA Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA Kurland C.G.;
RT "The genome sequence of Rickettsia prowazekii and the origin of
RT mitochondria.";
RL Nature 396:133-140(1998).
CC -!- FUNCTION: Responsible for the release of ribosomes from messenger RNA
CC at the termination of protein biosynthesis. May increase the efficiency
CC of translation by recycling ribosomes from one round of translation to
CC another. {ECO:0000255|HAMAP-Rule:MF_00040}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00040}.
CC -!- SIMILARITY: Belongs to the RRF family. {ECO:0000255|HAMAP-
CC Rule:MF_00040}.
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DR EMBL; AJ235270; CAA14622.1; -; Genomic_DNA.
DR PIR; G71725; G71725.
DR RefSeq; NP_220545.1; NC_000963.1.
DR RefSeq; WP_004595870.1; NC_000963.1.
DR AlphaFoldDB; Q9ZE08; -.
DR SMR; Q9ZE08; -.
DR STRING; 272947.RP154; -.
DR EnsemblBacteria; CAA14622; CAA14622; CAA14622.
DR GeneID; 57569283; -.
DR KEGG; rpr:RP154; -.
DR PATRIC; fig|272947.5.peg.159; -.
DR eggNOG; COG0233; Bacteria.
DR HOGENOM; CLU_073981_2_1_5; -.
DR OMA; FNPMNNG; -.
DR Proteomes; UP000002480; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006415; P:translational termination; IEA:UniProtKB-UniRule.
DR CDD; cd00520; RRF; 1.
DR Gene3D; 1.10.132.20; -; 1.
DR HAMAP; MF_00040; RRF; 1.
DR InterPro; IPR002661; Ribosome_recyc_fac.
DR InterPro; IPR023584; Ribosome_recyc_fac_dom.
DR InterPro; IPR036191; RRF_sf.
DR PANTHER; PTHR20982; PTHR20982; 1.
DR Pfam; PF01765; RRF; 1.
DR SUPFAM; SSF55194; SSF55194; 1.
DR TIGRFAMs; TIGR00496; frr; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Protein biosynthesis; Reference proteome.
FT CHAIN 1..186
FT /note="Ribosome-recycling factor"
FT /id="PRO_0000167529"
SQ SEQUENCE 186 AA; 21044 MW; CBB6F90AD5A807D7 CRC64;
MEKDNLKKIL QEKMEKAIKV LGNELKGLRT GRASINFLDS VTVEAYGSKI PLSQVASLST
PDARTINVQV WDKSMVSSVE KGITIANLGL THATDGQLIR LPIPSLTEER RKELVKLAHK
YGEETKISLR NIRRDGIEEL KKLEKDNIIV KDEYHNLSEQ IQKLTDEYSS KVDSAIKQKE
QEIMTV