AVT1B_ARATH
ID AVT1B_ARATH Reviewed; 540 AA.
AC F4JE35; Q9SV32;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2017, sequence version 2.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Amino acid transporter AVT1B {ECO:0000305};
DE Short=AtAvt1B {ECO:0000303|PubMed:27925655};
GN Name=AVT1B {ECO:0000303|PubMed:27925655};
GN OrderedLocusNames=At3g54830 {ECO:0000312|Araport:AT3G54830};
GN ORFNames=F28P10.190 {ECO:0000312|EMBL:CAB41101.1},
GN T5N23.1 {ECO:0000312|EMBL:AL138650};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=27925655; DOI=10.1002/1873-3468.12507;
RA Fujiki Y., Teshima H., Kashiwao S., Kawano-Kawada M., Ohsumi Y.,
RA Kakinuma Y., Sekito T.;
RT "Functional identification of AtAVT3, a family of vacuolar amino acid
RT transporters, in Arabidopsis.";
RL FEBS Lett. 591:5-15(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Amino acid/auxin permease (AAAP) (TC 2.A.18.5) subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AEE79297.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=ANM64194.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB41101.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL049655; CAB41101.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL138650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002686; AEE79297.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; ANM64194.1; ALT_SEQ; Genomic_DNA.
DR PIR; T06737; T06737.
DR RefSeq; NP_001326240.1; NM_001339700.1.
DR RefSeq; NP_191043.2; NM_115340.3.
DR AlphaFoldDB; F4JE35; -.
DR SMR; F4JE35; -.
DR STRING; 3702.AT3G54830.1; -.
DR PaxDb; F4JE35; -.
DR PeptideAtlas; F4JE35; -.
DR PRIDE; F4JE35; -.
DR ProteomicsDB; 240936; -.
DR GeneID; 824648; -.
DR KEGG; ath:AT3G54830; -.
DR Araport; AT3G54830; -.
DR TAIR; locus:2082652; AT3G54830.
DR eggNOG; KOG1303; Eukaryota.
DR HOGENOM; CLU_009646_1_0_1; -.
DR InParanoid; F4JE35; -.
DR OrthoDB; 570025at2759; -.
DR PRO; PR:F4JE35; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; F4JE35; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013057; AA_transpt_TM.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..540
FT /note="Amino acid transporter AVT1B"
FT /id="PRO_0000440103"
FT TRANSMEM 155..175
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 332..352
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 367..387
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 412..432
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..474
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 478..500
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 511..531
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 58234 MW; 4BD092EA37355FF8 CRC64;
MNHSTSDQSL YIESDDGDDE RKHLSDDEDD DGTLSDTSDA YNQNQHHLSK ASPYSTAWPK
SYRQSIDMFG SVPSPNLGFL ANSSMSRRGS SFMSSTLTRR HTPESLPCVT KPLLEDEEAP
KHKLSTHSLL PSKPSSSMVV SHDMGISNDS SFGQAVLNGV NVLCGVGILS TPYAVKEGGW
LGLIILFAFG ILCFYTGLLL RYCLDSHPDV QTYPDIGHAA FGSTGRILVS VILYMELYAM
SVEYIILEGD NLSSMFPNAS LSIGGFHLDA PRLFALLTTL AVLPTVWLRD LSVLSYISAG
GVIASVLVVL CLFWVGLVDD VGIHSKGTPL NLATLPVSVG LYGYCYSGHG VFPNIYTSMA
KPSQFSAVLL ASFGICTLMY AGVAVMGYSM FGESTESQFT LNLPQDLVAS KIALWTTVVN
PFTKYALTLS PVAMSLEELI PSNYGKSRFY AIAIRSALAI STLLVGLAIP FFGLVMSLIG
SFLTMLITLI LPPACFLSIL RKKVTPTQVT ICILIMTVGA VCSVIGTYSA LAKIIEKLNT
